Tandy Warnow

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Tandy Warnow
Tandy Warnow
Tandy Warnow speaking at the Intelligent Systems for Molecular Biology (ISMB) conference in 2018
Born
Tandy Jo Warnow
Alma materUniversity of California, Berkeley (BS, PhD)
SpouseGeorge Chacko
Children2
Awards
Scientific career
Fields
Simon Tavare[citation needed]
Doctoral studentsLuay Nakhleh[3]
Websitetandy.cs.illinois.edu Edit this at Wikidata

Tandy Warnow is an American computer scientist and Grainger Distinguished Chair in Engineering at the

evolutionary trees, both in biology and in historical linguistics, and also for multiple sequence alignment methods.[6]

Biography

Warnow did both her undergraduate and graduate studies in mathematics at the

Richard Karp, Manuel Blum, Dan Gusfield, and David Gale.[2]

Research and career

After

University of Illinois at Urbana–Champaign (UIUC), where she is the Grainger Distinguished Chair in Engineering and Associate Head of the Department of Computer Science. Warnow has courtesy appointments in the Departments of Animal Biology, Bioengineering, Electrical and Computer Engineering, Entomology, Mathematics, Plant Biology, and Statistics.[5][7]

In 1995, research by Warnow,

Indo-Hittite hypothesis according to which the first of these subdivisions to separate from the rest of the Indo-European languages were the Anatolian languages. Their results also support the Graeco-Armenian hypothesis, according to which the Armenian language and Greek language form a subfamily of Indo-European. They fit the Germanic languages into the evolutionary tree of Indo-European languages, previously considered problematic, by hypothesizing that the Proto-Germanic language was closely related to the Balto-Slavic languages but then became modified by westward migrations of the Germanic tribes which led them into contact with Italic and Celtic speakers.[8] This perfect phylogeny approach was later extended by Warnow and colleagues to allow for undetected borrowing between languages, so that language evolution is modelled with a network rather than a tree.[9]

In 2009, Warnow and her colleagues released their SATé software for co-estimating biological multiple sequence alignments and evolutionary trees.[10] Their software is based less strongly on firm mathematical principles than some previous co-estimation methods (such as BAli-Phy[11]), but is significantly faster, allowing the fast construction of highly accurate trees and alignments for thousands of species. In comparison, the slow performance of previous methods limited them to only comparing dozens of species at a time.[12][13]

Her work since 2014 has focused on three topics: scaling multiple sequence alignments to ultra-large datasets, species tree estimation using multiple genes (and addressing gene tree heterogeneity due to incomplete lineage sorting), and metagenomics. Her major contributions in these topics include the PASTA method for co-estimation of alignments and trees, which improves on SATé, and can produce highly accurate alignments with up to 1,000,000 sequences.[14] She has also developed the ASTRAL method for species tree estimation, which is a statistically consistent method for constructing species trees in the presence of incomplete lineage sorting.[15]

Awards and honors

Warnow was named a Grainger Distinguished Chair in Engineering in 2020 and Founder Professor of Engineering in 2014 (both at UIUC), and the David Bruton Jr. Centennial Professorship in Computer Science at the University of Texas at Austin in 2010.[5] Warnow also received a John Simon Guggenheim Foundation Fellowship in 2011, a Radcliffe Institute Fellowship in 2003, a David and Lucile Packard Foundation Fellowship in 1996, and the NSF Young Investigator Award in 1994.[5] In 2015, she was named a Fellow of Association for Computing Machinery (ACM) "For contributions to mathematical theory, algorithms, and software for large-scale molecular phylogenetics and historical linguistics".[16] In 2017, she was elected as a Fellow of the International Society for Computational Biology (ISCB).[17] She was named to the 2021 class of Fellows of the American Association for the Advancement of Science.[18]

Personal life

Warnow's mother was noted archivist

Kimmen Sjolander, a bioinformatics researcher and emeritus faculty member at the University of California. She is married to George Chacko, a Research Associate Professor in Computer Science at UIUC's Grainger College of Engineering,[20] and they have two children together, daughters Kristin and Menaka.[19]

References

  1. ^ Tandy Warnow publications indexed by Google Scholar Edit this at Wikidata
  2. ^
    ProQuest 303937362
    .
  3. ^ Nakhleh, Luay (2004). Phylogenetic networks (PhD thesis). University of Texas at Austin.
    hdl:2152/2126
    .
  4. ^ Tandy Warnow's Official website Edit this at Wikidata
  5. ^ a b c d "Tandy Warnow Curriculum vitae" (PDF)., retrieved 2020-09-10.
  6. ISBN 9781107184718
  7. ^ Tandy Jo Warnow at the Mathematics Genealogy Project
  8. New York Times
    .
  9. S2CID 162958
    .
  10. S2CID 8667974
    .
  11. PMID 16679334
    .
  12. ^ "Method For Computing Evolutionary Trees Could Revolutionize Evolutionary Biology", ScienceDaily, June 18, 2009.
  13. ^ Kloc, Joe (July 1, 2009), "How to build a better tree of life: An unconventional approach to analyzing molecular sequences allows researchers to construct larger evolutionary trees", Seed, archived from the original on July 4, 2009.
  14. PMID 25549288
    .
  15. PMID 26072508
    .
  16. ^ "ACM Fellows Named for Computing Innovations that Are Advancing Technology in the Digital Age". ACM. 8 December 2015. Archived from the original on 9 December 2015. Retrieved 9 December 2015.
  17. ^ "February 13, 2017: The International Society for Computational Biology Names Seven Members as the ISCB Fellows Class of 2017". www.iscb.org. Retrieved 13 February 2017.
  18. ^ "2021 Fellows". American Association for the Advancement of Science. Retrieved 2022-01-28.
  19. ^
    University of Illinois at Urbana–Champaign. Archived
    from the original on 2021-07-25. Retrieved 2023-04-17.
  20. University of Illinois at Urbana–Champaign. Archived
    from the original on 2023-01-28. Retrieved 2023-04-17.

External links
Retrieved from "https://en.wikipedia.org/w/index.php?title=Tandy_Warnow&oldid=1211550582"