Technetium (99mTc) nofetumomab merpentan
Fab fragment | |
| Source | Mouse |
|---|---|
| Clinical data | |
| Trade names | Verluma |
| ATC code |
|
| Pharmacokinetic data | |
| Elimination half-life | 10.5 hours |
| Excretion | renal (64%) |
| Identifiers | |
| CAS Number | |
| ChemSpider |
|
| UNII | |
  (what is this?) (verify) | |
Technetium (99mTc) nofetumomab merpentan (trade name Verluma) is a
radioisotope technetium-99m (99mTc).[3]
Nofetumomab
Nofetumomab is an antibody fragment that recognises the pancarcinoma glycoprotein antigen
MS4A1[5]
It is the Fab part of murine MAb NR-LU-10.[6]
Merpentan
The chelator part : merpentan is a
phenthioate ligand, 2,3,5,6-tetrafluorophenyl-4,5-bis-5-[1-ethoxyethyl]-thioacetoamidopentanoate.[6]
Phenthioate
Phenthioate is an insecticide (Cidial) = O,o-dimethyl-S-(carbethoxy-phenylmethyl)dithiophosphate[7]
References
- PMID 10634533.
- PMID 9298295.
- ^ "International Nonproprietary Names (INN) for pharmaceutical substances" (PDF). Geneva: World Health Organization. 2002. Archived from the original (PDF) on July 3, 2011.
- ISBN 978-0-08-047950-7.
- ^ "Anti-MS4A1 Therapeutic Antibody (Technetium (99MTC) Nofetumomab Merpentan)". Creative BioLabs.
- ^ a b Mudd E (27 February 2015). "Monoclonal Antibody Radionuclide Test Kits". Pharmacological Sciences.
- ^ US 3934010, Drabek J, Varsanyi D, "Insecticidal composition and method utilizing phosphoric acid phenylsulphonamide esters", issued 20 January 1976, assigned to Ciba Geigy Corporation
 | This monoclonal antibody–related article is a stub. You can help Wikipedia by expanding it. |