Testicular receptor 4
Testicular receptor 4 also known as NR2C2 (nuclear receptor subfamily 2, group C, member 2) is a protein that in humans is encoded by the NR2C2 gene.[5][6][7]
The testicular receptor 4 is a member of the nuclear receptor family of transcription factors.
Interactions
Testicular receptor 4 has been shown to
interact
with
See also
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000177463 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000005893 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: NR2C2".
- PMID 8016112.
- PMID 8661150.
- PMID 10611280.
- PMID 11844790.
- PMID 12522137.
Further reading
- Hirose T, Fujimoto W, Tamaai T, Kim KH, Matsuura H, Jetten AM (Dec 1994). "TAK1: molecular cloning and characterization of a new member of the nuclear receptor superfamily". Molecular Endocrinology. 8 (12): 1667–80. S2CID 24842898.
- Young WJ, Smith SM, Chang C (Jan 1997). "Induction of the intronic enhancer of the human ciliary neurotrophic factor receptor (CNTFRalpha) gene by the TR4 orphan receptor. A member of steroid receptor superfamily". The Journal of Biological Chemistry. 272 (5): 3109–16. PMID 9006963.
- Lee CH, Chinpaisal C, Wei LN (Sep 1998). "A novel nuclear receptor heterodimerization pathway mediated by orphan receptors TR2 and TR4". The Journal of Biological Chemistry. 273 (39): 25209–15. PMID 9737983.
- Lee YF, Shyr CR, Thin TH, Lin WJ, Chang C (Dec 1999). "Convergence of two repressors through heterodimer formation of androgen receptor and testicular orphan receptor-4: a unique signaling pathway in the steroid receptor superfamily". Proceedings of the National Academy of Sciences of the United States of America. 96 (26): 14724–9. PMID 10611280.
- Wang X, Yeh S, Wu G, Hsu CL, Wang L, Chiang T, Yang Y, Guo Y, Chang C (Nov 2001). "Identification and characterization of a novel androgen receptor coregulator ARA267-alpha in prostate cancer cells". The Journal of Biological Chemistry. 276 (44): 40417–23. PMID 11509567.
- Yeung KC, Rose DW, Dhillon AS, Yaros D, Gustafsson M, Chatterjee D, McFerran B, Wyche J, Kolch W, Sedivy JM (Nov 2001). "Raf kinase inhibitor protein interacts with NF-kappaB-inducing kinase and TAK1 and inhibits NF-kappaB activation". Molecular and Cellular Biology. 21 (21): 7207–17. PMID 11585904.
- Shyr CR, Hu YC, Kim E, Chang C (Apr 2002). "Modulation of estrogen receptor-mediated transactivation by orphan receptor TR4 in MCF-7 cells". The Journal of Biological Chemistry. 277 (17): 14622–8. PMID 11844790.
- Tanabe O, Katsuoka F, Campbell AD, Song W, Yamamoto M, Tanimoto K, Engel JD (Jul 2002). "An embryonic/fetal beta-type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer". The EMBO Journal. 21 (13): 3434–42. PMID 12093744.
- Yang Y, Wang X, Dong T, Kim E, Lin WJ, Chang C (Feb 2003). "Identification of a novel testicular orphan receptor-4 (TR4)-associated protein as repressor for the selective suppression of TR4-mediated transactivation". The Journal of Biological Chemistry. 278 (9): 7709–17. PMID 12486131.
- Lin WJ, Li J, Lee YF, Yeh SD, Altuwaijri S, Ou JH, Chang C (Mar 2003). "Suppression of hepatitis B virus core promoter by the nuclear orphan receptor TR4". The Journal of Biological Chemistry. 278 (11): 9353–60. PMID 12522137.
- Takaesu G, Surabhi RM, Park KJ, Ninomiya-Tsuji J, Matsumoto K, PMID 12547194.
- Inui S, Lee YF, Chang E, Shyr CR, Chang C (Feb 2003). "Differential and bi-directional regulation between TR2/TR4 orphan nuclear receptors and a specific ligand mediated-peroxisome proliferator-activated receptor alpha in human HaCaT keratinocytes". Journal of Dermatological Science. 31 (1): 65–71. PMID 12615366.
- Ishitani T, Takaesu G, Ninomiya-Tsuji J, Shibuya H, Gaynor RB, Matsumoto K (Dec 2003). "Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling". The EMBO Journal. 22 (23): 6277–88. PMID 14633987.
- Cheung PC, Nebreda AR, Cohen P (Feb 2004). "TAB3, a new binding partner of the protein kinase TAK1". The Biochemical Journal. 378 (Pt 1): 27–34. PMID 14670075.
- Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, Croughton K, Cruciat C, Eberhard D, Gagneur J, Ghidelli S, Hopf C, Huhse B, Mangano R, Michon AM, Schirle M, Schlegl J, Schwab M, Stein MA, Bauer A, Casari G, Drewes G, Gavin AC, Jackson DB, Joberty G, Neubauer G, Rick J, Kuster B, Superti-Furga G (Feb 2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nature Cell Biology. 6 (2): 97–105. S2CID 11683986.
External links
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