The Proteolysis Map
 | This article reads like a press release or a news article and may be largely based on routine coverage. (December 2019) |
The Proteolysis MAP (PMAP) was an integrated web resource focused on proteases.[1] Its domain now links to a scam/spam browser extender.
Rationale
PMAP was designed to aid the protease researchers in reasoning about
History and funding
PMAP was originally created at the
Focal point
Proteases are a class of
Goal
Proteolytic pathways, or proteolysis, are the series of events controlled by proteases that occur in response to specific stimuli. The clotting of blood and production of insulin can be viewed as proteolytic pathways. The activation, regulation and inhibition of the protein are protease reactions to changing glucose levels and trigger other proteases downstream.
Database content
PMAP integrates five databases.
ProteaseDB and SubstrateDB, are driven by an automated annotation pipeline that generates dynamic 'Molecule Pages', rich in molecular information. CutDB
Usage
Popular destinations in PMAP are Protease Molecule Pages and Substrate Molecule Pages. Protease Molecule Pages show recent news in
See also
References
- PMID 18842634.
- ^ Igarashi Y, Eroshkin A, Gramatikova S, Gramatikoff K, Zhang Y, Smith JW, Osterman AL, Godzik A. CutDB: a proteolytic event database. Nucleic Acids Research. 2007 D546-9
External links
- Proteases at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- Official website
- Proteolysis Cut Site database - curated expert annotation from users
- Protease cut sites graphical interface
- Protease cutting predictor
- Merops - the peptidase database
| Genomics | |
|---|---|
| Bioinformatics |
|
| Structural biology |
|
| Research tools |
|
| Organizations | |
