Thomas Bartholin

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Thomas Bartholin
Denmark-Norway
Died4 December 1680 (aged 64)
Copenhagen
NationalityDanish
Alma materUniversity of Padua
Known forLymphatic system
Scientific career
FieldsMedicine
InstitutionsUniversity of Copenhagen
Academic advisorsJohannes Walaeus

Thomas Bartholin (

Latinized as Thomas Bartholinus; 20 October 1616 – 4 December 1680) was a Danish physician, mathematician, and theologian. He discovered the lymphatic system in humans and advanced the theory of refrigeration anesthesia
, being the first to describe it scientifically.

Thomas Bartholin came from a family that has become famous for its pioneering scientists, twelve of whom became professors at the University of Copenhagen. Three generations of the Bartholin family made significant contributions to anatomical science and medicine in the 17th and 18th centuries: Thomas Bartholin's father, Caspar Bartholin the Elder (1585–1629), his brother Rasmus Bartholin (1625–1698), and his son Caspar Bartholin the Younger (1655–1738).[1] Thomas Bartholin's son Thomas Bartholin the Younger [da] (1659–1690) became a professor of history at the University of Copenhagen and was later appointed royal antiquarian and secretary to the Royal Archives.[2]

Personal life

Thomas Bartholin was the second of the six sons of Caspar Bartholin the Elder, a physician born in

blood circulation and on the lymphatic system
.

Bartholin visited the Italian botanist

Vor Frue Kirke
(Church of Our Lady).

The Bartholinsgade, a street in Copenhagen, is named for the family. Nearby is the Bartholin Institute (Bartholin Institutet). One of the buildings of the

University of Aarhus
is named after him.

Contributions to medical research

In December 1652, Bartholin published the first full description of the human

Niels Stensen
or Steno became Bartholin's most famous pupil.

Thomas' publication De nivis usu medico observationes variae Chapter XXII, contains the first known mention of refrigeration

anaesthesia, a technique whose invention Thomas Bartholin credits to the Italian Marco Aurelio Severino of Naples.[5]
According to Bartholin, Severino was the first to present the use of freezing mixtures of snow and ice (1646), and Thomas Bartholin initially learnt about the technique from him during a visit to Naples.

trisomy 13, was first described by Bartholin in 1656.[6][7]

Caspar Bartholin the Elder, Thomas Bartholin's father; his brother Rasmus Bartholin; and his son Caspar Bartholin the Younger (who first described "

Bartholin's glands"), all contributed to the practice of modern medicine through their discoveries of important anatomical structures and phenomena.[1] Bartholin the Elder started his tenure as professor at Copenhagen University in 1613, and over the next 125 years, the scientific accomplishments of the Bartholins while serving on the medical faculty of the University of Copenhagen
won international acclaim and contributed to the reputation of the institution.

Selected works

Antiquitatum veteris puerperii synopsis, 1676
  • Historiarum anatomicarum rariorum [...] (Case histories of unusual anatomical and clinical structures, including descriptions and illustrations of anomalies and normal structures)
  • De unicornu. Padua, 1645.
  • De Angina Puerorum Campaniae Siciliaeque Epidemica Exercitationes. Paris, 1646.
  • De lacteis thoracicis in homine brutisque nuperrime observatis historia anatomica at Google Books, Copenhagen: M. Martzan, 1652 (Bartholin's discovery of the thoracic duct).
  • Vasa lymphatica nuper Hafniae in animalibus inventa et hepatis exsequiae. Hafniae (Copenhagen), Petrus Hakius, 1653.
  • Vasa lymphatica in homine nuper inventa. Hafniae (Copenhagen), 1654.
  • Historarium anatomicarum rariorum centuria I-VI. Copenhagen, 1654–1661.
  • Anatomia. The Hague. Ex typographia Adriani Vlacq, 1655.
  • Dispensarium hafniense. Copenhagen, 1658.
  • De nivis usu medico observationes variae. Accessit D. Erasmi Bartholini de figura nivis dissertatio. With a book by Rasmus Bartholin. Copenhagen: Typis Matthiase Godichii, sumptibus Petri Haubold, 1661. (Contains the first known mention of refrigeration anaesthesia)
  • Cista medica hafniensis. Copenhagen, 1662.
  • De pulmonum substantia et motu. Copenhagen, 1663.
  • De insolitis partus humani viis. Copenhagen, 1664.
  • De medicina danorum domestica. Copenhagen, 1666.
  • De flammula cordis epistola. Copenhagen, 1667.
  • Orationes et dissertationes omnino varii argumenti. Copenhagen, 1668.
  • Carmina varii argumenti. Copenhagen, 1669.
  • De medicis poetis dissertatio. Hafinae, apud D. Paulli, 1669.
  • De bibliothecae incendio. Copenhagen, 1670.
  • De morbis biblicis miscellanea medica. Francofurti, D. Paulli, 1672.
  • De cruce Christi hypomnemata IV, Typis Andreae ab Hoogenhuysen, Vesaliae (Wesel), 1673.
  • Acta medica et philosophica. 1673–1680.

References

  1. ^ a b Hill, Robert V. (2007) "A Glimpse of Our Past – The contributions of the Bartholin family to the study and practice of clinical anatomy". Clinical Anatomy, Volume 20, Issue 2 (March 2007), pp. 113 – 115. Retrieved 22 February 2007.
  2. ^ Jónsson, Már (2012). Arnas Magnæus Philologus (1663–1730). [Odense]: University Press of Southern Denmark. pp. 48–49.
  3. ^ Detmar, Michael and Mihaela Skobe (2000). "Structure, Function, and Molecular Control of the Skin Lymphatic System". Journal of Investigative Dermatology Symposium Proceedings (2000) 5, 14–19. Retrieved 22 February 2007.
  4. ^ Eriksson, G. (2004). Svensk medicinhistorisk tidskrift, 2004;8(1):39-44. In Swedish. English abstract at Olaus Rudbeck as scientist and professor of medicine, U.S. National Library of Medicine. Retrieved 22 February 2007.
  5. ^ De nivis, p. 132, p. 132, at Google Books : " nix affricata induit stuporem. Id me docuit Marcus Aurelius Severinus in Gymnasio Neapolitano ".
  6. Who Named It?
  7. ^ Bartholinus, Thomas (1656). Historiarum anatomicarum rariorum centuria III et IV. Ejusdem cura accessere observationes anatomicae. The Hague: Vlacq. p. 95.

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