Thyroid follicular cell
|Thyroid follicular cell|
thyroxine (T4) and triiodothyronine (T3).
|Anatomical terms of microanatomy|
Thyroid follicular cells (also called thyroid epithelial cells or thyrocytes
Thyroid follicular cells form a simple
Calcitonin-producing parafollicular cells are also found along the basement membrane of the thyroid follicle, interspersed between follicular cells; and in spaces between the spherical follicles. Parafollicular cells can be distinguished from follicular cells based on their lighter staining cytoplasm using H&E.
Their embryologic origin is from a median endodermal mass in the region of the tongue (foramen cecum) in contrast to parafollicular cells which arise from the 4th pharyngeal pouch.
Follicular cells take up
These thyroid hormones are transported throughout the body where they control metabolism (which is the conversion of oxygen and carbohydrates to energy). Every cell in the body depends upon thyroid hormones for regulation of their metabolism. The normal thyroid gland produces about 80% T4 and about 20% T3, however, T3 is about four times as potent as T4.
The transport of iodide into follicular cells is vital for the synthesis of the
- ^ Mescher, Anthony L. Junqueira's Basic Histology, 14th edition. Lange. p. 430.
- ISBN 1-4160-2328-3.
- PMID 9159113.
- Anatomy Atlases - Microscopic Anatomy, plate 15.287
- Histology image: 14302loa – Histology Learning System at Boston University