Toothache
Toothache | |
---|---|
Other names | Odontalgia,[1] dentalgia,[1] odontodynia,[1] odontogenic pain[2]: 396 |
"Thou hell o' a' diseases" – William Hole's illustration for Robert Burns' poem "Address to the Toothache" (1897, poem c. 1786). | |
Specialty | Dentistry |
Toothache, also known as dental pain or tooth pain,
Common causes include
Pulpitis is reversible when the pain is mild to moderate and lasts for a short time after a stimulus (for instance cold); or irreversible when the pain is severe, spontaneous, and lasts a long time after a stimulus. Left untreated, pulpitis may become irreversible, then progress to
Proper
Causes
Toothache may be caused by dental (odontogenic) conditions (such as those involving the dentin-pulp complex or
Both the pulp and periodontal ligament have
For instance, the periodontal ligament can detect the pressure exerted when biting on something smaller than a grain of sand (10–30 µm).[14]: 48 When a tooth is intentionally stimulated, about 33% of people can correctly identify the tooth, and about 20% cannot narrow the stimulus location down to a group of three teeth.[11]: 31 Another typical difference between pulpal and periodontal pain is that the latter is not usually made worse by thermal stimuli.[6]: 125–135
Dental
Pulpal
The majority of pulpal toothache falls into one of the following types; however, other rare causes (which do not always fit neatly into these categories) include
Pulpitis
Because the pulp is encased in a rigid outer shell, there is no space to accommodate swelling caused by inflammation. Inflammation therefore increases pressure in the pulp system, potentially compressing the blood vessels which supply the pulp. This may lead to ischemia (lack of oxygen) and necrosis (tissue death). Pulpitis is termed reversible when the inflamed pulp is capable of returning to a state of health, and irreversible when pulp necrosis is inevitable.[11]: 36–37
Reversible pulpitis is characterized by short-lasting pain triggered by cold and sometimes heat.[13] The symptoms of reversible pulpitis may disappear, either because the noxious stimulus is removed, such as when dental decay is removed and a filling placed, or because new layers of dentin (tertiary dentin) have been produced inside the pulp chamber, insulating against the stimulus. Irreversible pulpitis causes spontaneous or lingering pain in response to cold.[16]: 619–627
Dentin hypersensitivity
Dentin hypersensitivity is a sharp, short-lasting dental pain occurring in about 15% of the population,[17] which is triggered by cold (such as liquids or air), sweet or spicy foods, and beverages.: 510
Many topical treatments for dentin hypersensitivity are available, including desensitizing toothpastes and protective varnishes that coat the exposed dentin surface.[17] Treatment of the root cause is critical, as topical measures are typically short lasting.[11]: 510 Over time, the pulp usually adapts by producing new layers of dentin inside the pulp chamber called tertiary dentin, increasing the thickness between the pulp and the exposed dentin surface and lessening the hypersensitivity.[11]: 510
Periodontal
In general, chronic periodontal conditions do not cause any pain. Rather, it is acute inflammation which is responsible for the pain.[19]
Apical periodontitis
The periodontal ligament becomes inflamed and there may be pain when biting or tapping on the tooth. On an X-ray, bone resorption appears as a radiolucent area around the end of the root, although this does not manifest immediately.[11]: 228 Acute apical periodontitis is characterized by well-localized, spontaneous, persistent, moderate to severe pain.[6]: 125–135 The alveolar process may be tender to palpation over the roots. The tooth may be raised in the socket and feel more prominent than the adjacent teeth.[6]: 125–135
Food impaction
Food impaction occurs when food debris, especially fibrous food such as meat, becomes trapped between two teeth and is pushed into the gums during chewing.[6]: 125–135 The usual cause of food impaction is disruption of the normal interproximal contour or drifting of teeth so that a gap is created (an open contact). Decay can lead to collapse of part of the tooth, or a dental restoration may not accurately reproduce the contact point. Irritation, localized discomfort or mild pain and a feeling of pressure from between the two teeth results. The gingival papilla is swollen, tender and bleeds when touched. The pain occurs during and after eating, and may slowly disappear before being evoked again at the next meal,[nb 1] or relieved immediately by using a tooth pick or dental floss in the involved area.[6]: 125–135 A gingival or periodontal abscess may develop from this situation.[22]: 444–445
Periodontal abscess
A periodontal abscess (lateral abscess) is a collection of pus that forms in the gingival crevices, usually as a result of chronic periodontitis where the pockets are pathologically deepened greater than 3mm. A healthy gingival pocket will contain bacteria and some calculus kept in check by the immune system. As the pocket deepens, the balance is disrupted, and an acute inflammatory response results, forming pus. The debris and swelling then disrupt the normal flow of fluids into and out of the pocket, rapidly accelerating the inflammatory cycle. Larger pockets also have a greater likelihood of collecting food debris, creating additional sources of infection.[22]: 443
Periodontal abscesses are less common than apical abscesses, but are still frequent. The key difference between the two is that the pulp of the tooth tends to be alive, and will respond normally to pulp tests. However, an untreated periodontal abscess may still cause the pulp to die if it reaches the tooth apex in a
A variant of the periodontal abscess is the gingival abscess, which is limited to the gingival margin, has a quicker onset, and is typically caused by trauma from items such as a fishbone, toothpick, or toothbrush, rather than chronic periodontitis.[22]: 446–447 The treatment of a periodontal abscess is similar to the management of dental abscesses in general (see: Treatment). However, since the tooth is typically alive, there is no difficulty in accessing the source of infection and, therefore, antibiotics are more routinely used in conjunction with scaling and root planing.[24] The occurrence of a periodontal abscess usually indicates advanced periodontal disease, which requires correct management to prevent recurrent abscesses, including daily cleaning below the gumline to prevent the buildup of subgingival plaque and calculus.
Acute necrotizing ulcerative gingivitis
Common marginal
Pericoronitis
Occlusal trauma
Occlusal trauma often occurs when a newly placed dental restoration is built too "high", concentrating the biting forces on one tooth. Height differences measuring less than a millimeter can cause pain. Dentists, therefore, routinely check that any new restoration is in harmony with the bite and forces are distributed correctly over many teeth using articulating paper. If the high spot is quickly eliminated, the pain disappears and there is no permanent harm.[22]: 153, 753 Over-tightening of braces can cause periodontal pain and, occasionally, a periodontal abscess.[22]: 503
Alveolar osteitis
Alveolar osteitis is a complication of tooth extraction (especially lower wisdom teeth) in which the blood clot is not formed or is lost, leaving the socket where the tooth used to be empty, and bare bone is exposed to the mouth.[30] The pain is moderate to severe, and dull, aching, and throbbing in character. The pain is localized to the socket, and may radiate. It normally starts two to four days after the extraction, and may last 10–40 days.[15][27]: 122 [28]: 216–217 [30] Healing is delayed, and it is treated with local anesthetic dressings, which are typically required for five to seven days.[28]: 216–217 There is some evidence that chlorhexidine mouthwash used prior to extractions prevents alveolar osteitis.[30]
Combined pulpal-periodontal
Dental trauma and cracked tooth syndrome
Cracked tooth syndrome refers to a highly variable[31] set of pain-sensitivity symptoms that may accompany a tooth fracture, usually sporadic, sharp pain that occurs during biting or with release of biting pressure,[32] or relieved by releasing pressure on the tooth.[11]: 24 The term is falling into disfavor and has given way to the more generalized description of fractures and cracks of the tooth, which allows for the wide variations in signs, symptoms, and prognosis for traumatized teeth. A fracture of a tooth can involve the enamel, dentin, and/or pulp, and can be orientated horizontally or vertically.[11]: 24–25 Fractured or cracked teeth can cause pain via several mechanisms, including dentin hypersensitivity, pulpitis (reversible or irreversible), or periodontal pain. Accordingly, there is no single test or combination of symptoms that accurately diagnose a fracture or crack, although when pain can be stimulated by causing separation of the cusps of the tooth, it's highly suggestive of the disorder.[11]: 27–31 Vertical fractures can be very difficult to identify because the crack can rarely be probed[11]: 27 or seen on radiographs, as the fracture runs in the plane of conventional films (similar to how the split between two adjacent panes of glass is invisible when facing them).[11]: 28–9
When toothache results from dental trauma (regardless of the exact pulpal or periodontal diagnosis), the treatment and prognosis is dependent on the extent of damage to the tooth, the stage of development of the tooth, the degree of displacement or, when the tooth is avulsed, the time out of the socket and the starting health of the tooth and bone. Because of the high variation in treatment and prognosis, dentists often use trauma guides to help determine prognosis and direct treatment decisions.[33][34]
The prognosis for a cracked tooth varies with the extent of the fracture. Those cracks that are irritating the pulp but do not extend through the pulp chamber can be amenable to stabilizing dental restorations such as a crown or composite resin. Should the fracture extend though the pulp chamber and into the root, the prognosis of the tooth is hopeless.[11]: 25
Periodontic-endodontic lesion
Apical abscesses can spread to involve periodontal pockets around a tooth, and periodontal pockets cause eventual pulp necrosis via accessory canals or the apical foramen at the bottom of the tooth. Such lesions are termed periodontic-endodontic lesions, and they may be acutely painful, sharing similar signs and symptoms with a periodontal abscess, or they may cause mild pain or no pain at all if they are chronic and free-draining.[35] Successful root canal therapy is required before periodontal treatment is attempted.[22]: 49 Generally, the long-term prognosis of perio-endo lesions is poor.
Non-dental
Non-dental causes of toothache are much less common as compared with dental causes. In a toothache of neurovascular origin, pain is reported in the teeth in conjunction with a
Disorders of the maxillary sinus can be referred to the upper back teeth. The posterior, middle and anterior superior alveolar nerves are all closely associated with the lining of the sinus. The bone between the floor of the maxillary sinus and the roots of the upper back teeth is very thin, and frequently the apices of these teeth disrupt the contour of the sinus floor. Consequently, acute or chronic maxillary sinusitis can be perceived as maxillary toothache,[37] and neoplasms of the sinus (such as adenoid cystic carcinoma)[38]: 390 can cause similarly perceived toothache if malignant invasion of the superior alveolar nerves occurs.[39]: 72 Classically, sinusitis pain increases upon Valsalva maneuvers or tilting the head forward.[40]
Painful conditions which do not originate from the teeth or their supporting structures may affect the oral mucosa of the gums and be interpreted by the individual as toothache. Examples include neoplasms of the gingival or
Pathophysiology
A tooth is composed of an outer shell of
Enamel is not a vital tissue, as it lacks blood vessels, nerves, and living cells.[19] Consequently, pathologic processes involving only enamel, such as shallow cavities or cracks, tend to be painless.[19] Dentin contains many microscopic tubes containing fluid and the processes of odontoblast cells, which communicate with the pulp. Mechanical, osmotic, or other stimuli cause movement of this fluid, triggering nerves in the pulp (the "hydrodynamic theory" of pulp sensitivity).[20] Due to the close relationship between dentin and pulp, they are frequently considered together as the dentin-pulp complex.[44]: 118
The teeth and gums exhibit normal sensations in health. Such sensations are generally sharp, lasting as long as the stimulus.
The pain pathway is mostly transmitted via
Diagnosis
The diagnosis of toothache can be challenging,
Symptoms
The
From the history, indicators of pulpal, periodontal, a combination of both, or non-dental causes can be observed. Periodontal pain is frequently localized to a particular tooth, which is made much worse by biting on the tooth, sudden in onset, and associated with bleeding and pain when brushing. More than one factor may be involved in the toothache. For example, a pulpal abscess (which is typically severe, spontaneous and localized) can cause periapical periodontitis (which results in pain on biting). Cracked tooth syndrome may also cause a combination of symptoms. Lateral periodontitis (which is usually without any thermal sensitivity and sensitive to biting) can cause pulpitis and the tooth becomes sensitive to cold.[11]: 2–9
Non-dental sources of pain often cause multiple teeth to hurt and have an epicenter that is either above or below the jaws. For instance, cardiac pain (which can make the bottom teeth hurt) usually radiates up from the chest and neck, and sinusitis (which can make the back top teeth hurt) is worsened by bending over.[11]: 56, 61 As all of these conditions may mimic toothache, it is possible that dental treatment, such as fillings, root canal treatment, or tooth extraction may be carried out unnecessarily by dentists in an attempt to relieve the individual's pain, and as a result the correct diagnosis is delayed. A hallmark is that there is no obvious dental cause, and signs and symptoms elsewhere in the body may be present. As migraines are typically present for many years, the diagnosis is easier to make. Often the character of the pain is the differentiator between dental and non-dental pain.[citation needed]
Irreversible pulpitis progresses to pulp necrosis, wherein the nerves are non-functional, and a pain-free period following the severe pain of irreversible pulpitis may be experienced. However, it is common for irreversible pulpitis to progress to apical periodontitis, including an acute apical abscess, without treatment. As irreversible pulpitis generates an apical abscess, the character of the toothache may simply change without any pain-free period. For instance, the pain becomes well localized, and biting on the tooth becomes painful. Hot drinks can make the tooth feel worse because they expand the gases and likewise, cold can make it feel better, thus some will sip cold water.[11][15]
Examination
The clinical examination narrows the source down to a specific tooth, teeth, or a non-dental cause. Clinical examination moves from the outside to the inside, and from the general to the specific. Outside of the mouth, the
Sometimes the symptoms reported in the history are misleading and point the examiner to the wrong area of the mouth. For instance, sometimes people may mistake pain from pulpitis in a lower tooth as pain in the upper teeth, and vice versa. In other instances, the apparent examination findings may be misleading and lead to the wrong diagnosis and wrong treatment. Pus from a pericoronal abscess associated with a lower third molar may drain along the
Factors indicating infection include movement of fluid in the tissues during palpation (fluctuance), swollen lymph nodes in the neck, and fever with an oral temperature more than 37.7 °C.[citation needed]
Investigations
Any tooth that is identified, in either the history of pain or base clinical exam, as a source for toothache may undergo further testing for vitality of the dental pulp, infection, fractures, or periodontitis. These tests may include:[11]: 10–19
- Pulp sensitivity tests, usually carried out with a cotton wool test sensitivity, a second symptom should be present or a positive test before making a diagnosis.
- Radiographsutilized to find dental caries and bone loss laterally or at the apex.
- Assessment of biting on individual teeth (which sometimes helps to localize the problem) or the separate cusps (may help to detect cracked cusp syndrome).
Less commonly used tests might include trans-illumination (to detect congestion of the maxillary sinus or to highlight a crack in a tooth), dyes (to help visualize a crack), a test cavity, selective anaesthesia and laser doppler flowmetry.
-
Pulp sensibility test using ethyl chloride (cold stimulus)
-
Electric pulp tester
-
Plastic wedge to identify pain on biting from a fractured tooth
-
Transillumination demonstrating fracture
-
Decay (green) with apical abscess (blue)
-
Gutta-percha point indicating abscess origin
Establishing a diagnosis of nondental toothache is initially done by careful questioning about the site, nature, aggravating and relieving factors, and referral of the pain, then ruling out any dental causes. There are no specific treatments for nondental pain (each treatment is directed at the cause of the pain, rather than the toothache itself), but a dentist can assist in offering potential sources of the pain and direct the patient to appropriate care. The most critical nondental source is the radiation of
Differential diagnoses
Parameter | Dentin hypersensitivity[11]: 36 | Reversible pulpitis[11]: 36 | Irreversible pulpitis[11]: 36–37 | Pulp necrosis[11]: 37 | Apical periodontitis[11]: 37–38 | Periodontal abscess | Pericoronitis | Myofascial pain | Maxillary sinusitis |
---|---|---|---|---|---|---|---|---|---|
Site | Poorly localized | Poorly localized | Variable; localized or diffuse | No pain | Well localized | Usually well localized | Well localized, associated with partially impacted tooth | Diffuse, often over many muscles | Back teeth top jaw |
Onset | Gradual | Variable | Variable | From pain of reversible pulpitis to no pain in days | Gradual, typically follows weeks of thermal pain in tooth | Sudden, no episode of thermal sensitivity | Sudden | Very slow; weeks to months | Sudden |
Character | Sharp, quickly reversible | Sharp, shooting | Dull, continuous pain. Can also be sharp | No pain | Dull, continuous throbbing pain | Dull, continuous throbbing pain | Sharp, with continuous dull | Dull, aching | Dull, aching, occasional thermal sensitivity in back top teeth |
Radiation | Does not cross midline | Does not cross midline | Does not cross midline | N/A | Does not cross midline | Little, well localized | Moderate, into jaw/neck | Extensive, neck/temple | Moderate, into other facial sinus areas |
Associated symptoms | Patient may complain of receding gums and/or toothbrush abrasion cavities | Can follow restorative dental work or trauma | Follows period of pain that does not linger | Follows period of spontaneous pain | Tooth may feel raised in socket | May follow report of something getting "stuck" in gum | Tooth eruption ("cutting") or impacted tooth | Tension headaches, neck pain, periods of stress or episode of mouth open for long period | Symptoms of URTI |
Time pattern | Hypersensitivity as long as stimulus is applied; often worse in cold weather | Pain as long as stimulus is applied | Lingering pain to hot or cold or spontaneous pain | Absence of pain following days or weeks of intense, well localized pain | Pain on biting following constant dull, aching pain development | Dull ache with acute increase in pain when tooth is moved, minimal thermal sensitivity | Constant dull ache without stimulus | Spontaneous, worse with eating, chewing, or movement of jaw | Spontaneous, worse when head is tipped forward |
Exacerbating and relieving factors | Exacerbating: thermal, particularly cold | Exacerbating: thermal, sweet | Simple analgesics have little effect | Prolonged heat may elicit pain | Same as irreversible pulpitis, or no response to cold, lingering pain to hot, pain with biting or lying down | Tapping tooth makes worse, cleansing area may improve pain | Cleansing area can improve pain | Rest or ice makes pain better, movement and chewing make it worse | Tilting head forward, jarring movements (jumping) make pain worse |
Severity | Less severe than pulpitis | Severe, for short periods | Variable; pain dissipates until periapical tissue affected | Severe | Severe | Severe | Mild to severe | Mild to moderate | Mild to severe |
Effect on sleep | None | None usually | Disrupts sleep | None | Disrupts sleep | Variable, can disrupt sleep | If moderate to severe, will disrupt | Unusual | Unusual |
When it becomes extremely painful and decayed the tooth may be known as a
Prevention
Since most toothache is the result of
Management
There are many causes of toothache and its diagnosis is a specialist topic, meaning that attendance at a dentist is usually required. Since many cases of toothache are inflammatory in nature,
For the dentist, the goal of treatment generally is to relieve the pain, and wherever possible to preserve or restore function. The treatment depends on the cause of the toothache, and frequently a clinical decision regarding the current state and long-term prognosis of the affected tooth, as well as the individual's wishes and ability to cope with dental treatment, will influence the treatment choice. Often, administration of an intra-oral local anesthetic such as
Pulpitis and its sequalae
In pulpitis, an important distinction in regard to treatment is whether the inflammation is reversible or irreversible. Treatment of reversible pulpitis is by removing or correcting the causative factor. Usually, the decay is removed, and a sedative dressing is used to encourage the pulp to return to a state of health,
Reversible/irreversible pulpitis is a distinct concept from whether the tooth is restorable or unrestorable, e.g. a tooth may only have reversible pulpitis, but has been structurally weakened by decay or trauma to the point that it is impossible to restore the tooth in the long term.[citation needed]
Dental abscesses
A general principle concerning dental abscesses is ubi pus, ibi evacua ("where there is pus, drain it"), which applies to any case where there is a collection of pus in the tissues (such as a periodontal abscess, pericoronal abscess, or apical abscess). The pus within the abscess is under pressure, and the surrounding tissues are deformed and stretched to accommodate the swelling. This leads to a sensation of throbbing (often in time with the pulse) and constant pain. Pus may be evacuated via the tooth by drilling into the pulp chamber (an endodontic access cavity). Such a treatment is sometimes termed open drainage. Drainage can also be performed via the tooth socket, once the causative tooth is extracted. If neither of those measures succeeds, or they are impossible, incision and drainage may be required, in which a small incision is made in the soft tissues directly over the abscess at the most dependent point. A surgical instrument such as a pair of tweezers is gently inserted into the incision and opened, while the abscess is massaged to encourage the pus to drain out. Usually, the reduction in pain when the pus drains is immediate and marked as the built up pressure is relieved. If the pus drains into the mouth, there is usually a bad or offensive taste.[citation needed]
Antibiotics
Antibiotics tend to be extensively used for emergency dental problems.
Antibiotics tend to be used when local measures cannot be carried out immediately.
Prognosis
Most dental pain can be treated with routine dentistry. In rare cases, toothache can be a symptom representing a life-threatening condition, such as a deep neck infection (compression of the
Dental caries, if left untreated, follows a predictable
Epidemiology
In the United States, an estimated 12% of people reported that they had a toothache at some point in the six months before questioning.[11]: 40 Individuals aged 18–34 reported much higher rates toothache than those aged 75 or over.[29]: 6 In a survey of Australian schoolchildren, 12% had experienced toothache before the age of five, and 32% by the age of 12.[29]: 6 Dental trauma is extremely common and tends to occur more often in children than adults.[26]
Toothache may occur at any age, in any gender and in any geographic region. Diagnosing and relieving toothache is considered one of the main responsibilities of dentists.[5] Irreversible pulpitis is thought to be the most common reason that people seek emergency dental treatment.[51] Since dental caries associated with pulpitis is the most common cause, toothache is more common in populations that are at higher risk of dental caries. The prevalence of caries in a population is dependent upon factors such as diet (refined sugars), socioeconomic status, and exposure to fluoride (such as areas without water fluoridation).[29]: 6
History, society and culture
The first known mention of tooth decay and toothache occurs on a
In Christianity, Saint Apollonia is the patron saint of toothache and other dental problems. She was an early Christian martyr who was persecuted for her beliefs in Alexandria during the Imperial Roman age. A mob struck her repeatedly in the face until all her teeth were smashed. She was threatened with being burned alive unless she renounced Christianity, but she instead chose to throw herself onto the fire. Supposedly, toothache sufferers who invoke her name will find relief.[57]
In the 15th century, priest-physician Andrew Boorde describes a "deworming technique" for the teeth: "And if it [toothache] do come by worms, make a candle of wax with Henbane seeds and light it and let the perfume of the candle enter into the tooth and gape over a dish of cold water and then you may take the worms out of the water and kill them on your nail."[56]: 48–52
In the Elizabethan era, toothache was an ailment associated with lovers,[59] as in Massinger and Fletcher's play The False One. Toothache also appears in a number of William Shakespeare's plays, such as Othello and Cymbeline. In Much Ado About Nothing, Act III scene 2, when asked by his companions why he is feeling sad, a character replies that he has toothache so as not to admit the truth that he is in love. There is reference to "toothworm" as the cause of toothache and to tooth extraction as a cure ("draw it"). In Act V, scene 1, another character remarks: "For there was never yet philosopher That could endure the toothache patiently."[60] In modern parlance, this translates to the observation that philosophers are still human and feel pain, even though they claim they have transcended human suffering and misfortune.[61] In effect, the character is rebuking his friend for trying to make him feel better with philosophical platitudes.
The Scottish poet, Robert Burns wrote "Address to the Toothache" in 1786, inspired after he suffered from it. The poem elaborates on the severity of toothache, describing it as the "hell o' a' diseases" (hell of all diseases).[62]
A number of plants and trees include "toothache" in their common name. Prickly ash (Zanthoxylum americanum) is sometimes termed "toothache tree", and its bark, "toothache bark"; whilst Ctenium Americanum is sometimes termed "toothache grass", and Acmella oleracea is called "toothache plant". Pellitory (Anacyclus pyrethrum) was traditionally used to relieve toothache.[citation needed]
In
The phrase toothache in the bones is sometimes used to describe the pain in certain types of diabetic neuropathy.[65]: 1342
Notes
- ^ This pattern of pain should be distinguished from the "meal time syndrome" of certain salivary gland diseases.
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External links
- The dictionary definition of tootache at Wiktionary
- WebMD Dental Health & Toothaches
- Mayo Clinic Toothache First Aid
- U.S. National Library of Medicine: Toothaches