Toxicity category rating

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labeling, such as classification for restricted use and requirements for child-resistant packaging
.

In certain cases, statements based upon the Toxicity Category of the product as diluted for use are also permitted. A Toxicity Category is assigned for each of five types of acute exposure, as specified in the table below.[citation needed]

Overview

The four toxicity categories, from one to four are:

  • Toxicity category I is highly toxic and severely irritating,
  • Toxicity category II is moderately toxic and moderately irritating,
  • Toxicity category III is slightly toxic and slightly irritating,
  • Toxicity category IV is practically non-toxic and not an irritant.

Acute toxicity categories for pesticide products[1]

In the following table, the leftmost column lists the route of administration.

I II III IV
Oral LD50 Up to and including 50 mg/kg From 50 to 500 mg/kg From 500 to 5000 mg/kg Greater than 5000 mg/kg
Inhalation LC50 Up to and including 0.2 mg/L From 0.2 to 2 mg/L From 2. to 20 mg/L Greater than 20 mg/L
Dermal
LD50 		Up to and including 200 mg/kg From 200 to 2000 mg/kg From 2000 to 20,000 mg/kg Greater than 20,000 mg/kg
Eye Effects Corrosive; corneal opacity not reversible within 7 days Corneal opacity reversible within 7 days; irritation persisting for 7 days No corneal opacity; irritation reversible within 7 days No irritation.
Skin Effects Corrosive Severe irritation at 72 hours Moderate irritation at 72 hours Mild or slight irritation at 72 hours

References

  1. ^ "40 CFR 156.64: Toxicity Category" (PDF). Code of Federal Regulations. Office of the Federal Register. Retrieved 2009-04-30.
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