Troxerutin

Source: Wikipedia, the free encyclopedia.
Troxerutin
Clinical data
Other namesHydroxyethylrutoside (HER)
Pherarutin
Trihydroxyethylrutin
3',4',7-Tris[O-(2-hydroxyethyl)]rutin
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • 2-[3,4-bis(2-hydroxyethoxy)phenyl]-5-hydroxy-7-(2-hydroxyethoxy)-4-oxo-4H-chromen-3-yl 6-O-(6-deoxy-β-D-mannopyranosyl)-β-D-glucopyranoside
JSmol)
  • C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)Oc3c(=O)c4c(cc(cc4oc3c5ccc(c(c5)OCCO)OCCO)OCCO)O)O)O)O)O)O)O
  • InChI=1S/C33H42O19/c1-14-23(38)26(41)28(43)32(49-14)48-13-21-24(39)27(42)29(44)33(51-21)52-31-25(40)22-17(37)11-16(45-7-4-34)12-20(22)50-30(31)15-2-3-18(46-8-5-35)19(10-15)47-9-6-36/h2-3,10-12,14,21,23-24,26-29,32-39,41-44H,4-9,13H2,1H3/t14-,21+,23-,24+,26+,27-,28+,29+,32+,33-/m0/s1 ☒N
  • Key:IYVFNTXFRYQLRP-VVSTWUKXSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Troxerutin is a

Sophora japonica
, the Japanese pagoda tree.

It is used as a vasoprotective.[2]

Troxerutin has been shown in mice to reverse CNS insulin resistance and reduce reactive oxygen species induced by a high-cholesterol diet.[3]

References