Urea-containing cream
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Urea, also known as carbamide-containing cream,[
In adults side effects are generally few.[4] It may occasionally cause skin irritation.[1] Urea works in part by loosening dried skin.[5] Preparations generally contain 5 to 50% urea.[2][3]
Medical uses
Urea cream is indicated for debridement and promotion of normal healing of skin areas with hyperkeratosis, particularly where healing is inhibited by local skin infection, skin necrosis, fibrinous or itching debris or eschar.[5] Specific condition with hyperkeratosis where urea cream is useful include:
- Dry skin and rough skin[5]
- Dermatitis[5]
- Psoriasis[5]
- Ichthyosis[5]
- Eczema[5]
- Keratosis[5]
- Keratoderma[5]
- Corns[5]
- Calluses[5]
- Damaged, ingrown and devitalized nails[5]
Side effects
Common side effects of urea cream are:
In severe cases, there can be an
Mechanism of action
Urea in low doses is a humectant while at high doses (above 20%) it causes breakdown of protein in the skin.[10]
Urea dissolves the
References
- ^ ISBN 9789241547659.
- ^ ISBN 9780857111562.
- ^ a b c d "Urea topical medical facts from Drugs.com". www.drugs.com. Archived from the original on 18 January 2017. Retrieved 15 January 2017.
- ISBN 9783662451397. Archivedfrom the original on 2017-01-16.
- ^ a b c d e f g h i j k l m n "Urea Cream - FDA prescribing information, side effects and uses". www.drugs.com. Archived from the original on 18 January 2017. Retrieved 15 January 2017.
- ISBN 9780849375200. Archivedfrom the original on 2017-01-16.
- hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
- hdl:10665/345533. WHO/MHP/HPS/EML/2021.02.
- ^ a b c d e "Urea Cream (Consumer Information)". Drugs.com. May 4, 2011. Archived from the original on 2011-02-26.
- PMID 27293248.
External links
- "Urea". Drug Information Portal. U.S. National Library of Medicine.