Vagina

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Vagina
superficial inguinal lymph nodes
Identifiers
Latinvagina
MeSHD014621
TA98A09.1.04.001
TA23523
FMA19949
Anatomical terminology]

In

genital tract. In humans, it extends from the vestibule to the cervix. The outer vaginal opening is normally partly covered by a thin layer of mucosal tissue called the hymen. At the deep end, the cervix (neck of the uterus) bulges into the vagina. The vagina allows for copulation and birth. It also channels menstrual flow, which occurs in humans and closely related primates as part of the menstrual cycle
.

Although research on the vagina is especially lacking for different animals, its location, structure and size are documented as varying among species. Female mammals usually have two external openings in the

urinary tract and the vaginal opening for the genital tract. This is different from male mammals, who usually have a single urethral opening for both urination and reproduction. The vaginal opening is much larger than the nearby urethral opening, and both are protected by the labia in humans. In amphibians, birds, reptiles and monotremes, the cloaca
is the single external opening for the gastrointestinal, urinary, and reproductive tracts.

To accommodate smoother penetration of the vagina during sexual intercourse or other

sexually transmitted infections (STIs), the risk of which can be reduced by recommended safe sex practices. Other health issues
may also affect the human vagina.

The vagina and vulva have evoked strong reactions in societies throughout history, including negative perceptions and language, cultural

female sexuality, spirituality, or regeneration of life. In common speech
, the word vagina is often used to refer to the vulva or to the female genitals in general. By its dictionary and anatomical definitions, however, vagina refers exclusively to the specific internal structure, and understanding the distinction can improve knowledge of the female genitalia and aid in healthcare communication.

Etymology and definition

The term vagina is from Latin meaning "sheath" or "scabbard".[1] The vagina may also be referred to as the birth canal in the context of pregnancy and childbirth.[2][3] Although by its dictionary and anatomical definitions, the term vagina refers exclusively to the specific internal structure, it is colloquially used to refer to the vulva or to both the vagina and vulva.[4][5]

Using the term vagina to mean "vulva" can pose medical or legal confusion; for example, a person's interpretation of its location might not match another's interpretation of the location.[4][6] Medically, one description of the vagina is that it is the canal between the hymen (or remnants of the hymen) and the cervix, while a legal description is that it begins at the vulva (between the labia).[4] It may be that the incorrect use of the term vagina is due to not as much thought going into the anatomy of the female genitals as has gone into the study of male genitals, and that this has contributed to an absence of correct vocabulary for the external female genitalia among both the general public and health professionals. Because a better understanding of female genitalia can help combat sexual and psychological harm with regard to female development, researchers endorse correct terminology for the vulva.[6][7][8]

Structure

Gross anatomy

Diagram illustrating female pelvic anatomy
Pelvic anatomy including organs of the female reproductive system

The human vagina is an elastic, muscular canal that extends from the vulva to the cervix.[9][10] The opening of the vagina lies in the urogenital triangle. The urogenital triangle is the front triangle of the perineum and also consists of the urethral opening and associated parts of the external genitalia.[11] The vaginal canal travels upwards and backwards, between the urethra at the front, and the rectum at the back. Near the upper vagina, the cervix protrudes into the vagina on its front surface at approximately a 90 degree angle.[12] The vaginal and urethral openings are protected by the labia.[13]

When not

vaginal fornices); these are the anterior, posterior, right lateral, and left lateral fornices.[9][10] The posterior fornix is deeper than the anterior fornix.[10]

Supporting the vagina are its upper, middle, and lower third muscles and ligaments. The upper third are the

pelvic diaphragms.[19] The lower third may also be described as being supported by the perineal body and the pubovaginal part of the levator ani muscle.[16]

Vaginal opening and hymen

Vaginal opening located at 4

The vaginal opening (also known as the vaginal introitus)[20] is at the posterior end of the vulval vestibule, behind the urethral opening. The opening to the vagina is normally obscured by the labia minora (inner lips), but may be exposed after vaginal delivery.[10]

The

physical exercise. For these reasons, virginity cannot be definitively determined by examining the hymen.[21][22]

Variations and size

The length of the vagina varies among women of child-bearing age. Because of the presence of the cervix in the front wall of the vagina, there is a difference in length between the front wall, approximately 7.5 cm (2.5 to 3 in) long, and the back wall, approximately 9 cm (3.5 in) long.[10][23] During sexual arousal, the vagina expands both in length and width. If a woman stands upright, the vaginal canal points in an upward-backward direction and forms an angle of approximately 45 degrees with the uterus.[10][18] The vaginal opening and hymen also vary in size; in children, although the hymen commonly appears crescent-shaped, many shapes are possible.[10][24]

Development

Drawn anatomic illustration as described in caption
An illustration showing a cut-away portion of the vagina and upper female genital tract (only one ovary and fallopian tube shown). Circular folds (also called rugae) of vaginal mucosa can be seen.

The vaginal plate is the precursor to the vagina.[25] During development, the vaginal plate begins to grow where the fused ends of the paramesonephric ducts (Müllerian ducts) enter the back wall of the urogenital sinus as the sinus tubercle. As the plate grows, it significantly separates the cervix and the urogenital sinus; eventually, the central cells of the plate break down to form the vaginal lumen.[25] This usually occurs by the twenty to twenty-fourth week of development. If the lumen does not form, or is incomplete, membranes known as vaginal septae can form across or around the tract, causing obstruction of the outflow tract later in life.[25]

During sexual differentiation, without testosterone, the urogenital sinus persists as the vestibule of the vagina. The two urogenital folds of the genital tubercle form the labia minora, and the labioscrotal swellings enlarge to form the labia majora.[26][27]

There are conflicting views on the embryologic origin of the vagina. The majority view is Koff's 1933 description, which posits that the upper two-thirds of the vagina originate from the caudal part of the Müllerian duct, while the lower part of the vagina develops from the urogenital sinus.

Wolffian ducts.[29][31] Witschi's view is supported by research by Acién et al., Bok and Drews.[29][31] Robboy et al. reviewed Koff and Bulmer's theories, and support Bulmer's description in light of their own research.[30] The debates stem from the complexity of the interrelated tissues and the absence of an animal model that matches human vaginal development.[30][32] Because of this, study of human vaginal development is ongoing and may help resolve the conflicting data.[29]

Microanatomy

Micrograph of vaginal wall
Medium-power magnification micrograph of a H&E stained slide showing a portion of a vaginal wall. Stratified squamous epithelium and underling connective tissue can be seen. The deeper muscular layers are not shown. The black line points to a fold in the mucosa.

The vaginal wall from the lumen outwards consists firstly of a

mucosa of stratified squamous epithelium that is not keratinized, with a lamina propria (a thin layer of connective tissue) underneath it. Secondly, there is a layer of smooth muscle with bundles of circular fibers internal to longitudinal fibers (those that run lengthwise). Lastly, is an outer layer of connective tissue called the adventitia. Some texts list four layers by counting the two sublayers of the mucosa (epithelium and lamina propria) separately.[33][34]

The smooth muscular layer within the vagina has a weak contractive force that can create some pressure in the lumen of the vagina; much stronger contractive force, such as during childbirth, comes from muscles in the pelvic floor that are attached to the adventitia around the vagina.[35]

The lamina propria is rich in blood vessels and lymphatic channels. The muscular layer is composed of smooth muscle fibers, with an outer layer of longitudinal muscle, an inner layer of circular muscle, and oblique muscle fibers between. The outer layer, the adventitia, is a thin dense layer of connective tissue and it blends with loose connective tissue containing blood vessels, lymphatic vessels and nerve fibers that are between pelvic organs.[12][34][23] The vaginal mucosa is absent of glands. It forms folds (transverse ridges or rugae), which are more prominent in the outer third of the vagina; their function is to provide the vagina with increased surface area for extension and stretching.[9][10]

Close-up photograph of vagina
Folds of mucosa (or vaginal rugae) are shown in the front third of a vagina.

The epithelium of the ectocervix (the portion the uterine cervix extending into the vagina) is an extension of, and shares a border with, the vaginal epithelium.

mitochondria and other organelles.[38][42] The cells retain a usually high level of glycogen compared to other epithelial tissue in the body.[38]

Under the influence of maternal estrogen, the vagina of a newborn is lined by thick stratified squamous epithelium (or mucosa) for two to four weeks after birth. Between then to puberty, the epithelium remains thin with only a few layers of cuboidal cells without glycogen.[40][43] The epithelium also has few rugae and is red in color before puberty.[4] When puberty begins, the mucosa thickens and again becomes stratified squamous epithelium with glycogen containing cells, under the influence of the girl's rising estrogen levels.[40] Finally, the epithelium thins out from menopause onward and eventually ceases to contain glycogen, because of the lack of estrogen.[10][39][44]

Flattened squamous cells are more resistant to both abrasion and infection.

antibodies and other immune components can easily reach the surface.[45] The vaginal epithelium differs from the similar tissue of the skin. The epidermis of the skin is relatively resistant to water because it contains high levels of lipids. The vaginal epithelium contains lower levels of lipids. This allows the passage of water and water-soluble substances through the tissue.[45]

Keratinization happens when the epithelium is exposed to the dry external atmosphere.

pelvic organ prolapse, the mucosa may be exposed to air, becoming dry and keratinized.[46]

Blood and nerve supply

Blood is supplied to the vagina mainly via the

inguinal lymph nodes.[15][48] Ninety-five percent of the lymphatic channels of the vagina are within 3 mm of the surface of the vagina.[49]

Two main veins drain blood from the vagina, one on the left and one on the right. These form a network of smaller veins, the vaginal venous plexus, on the sides of the vagina, connecting with similar venous plexuses of the uterus, bladder, and rectum. These ultimately drain into the internal iliac veins.[15]

The nerve supply of the upper vagina is provided by the sympathetic and parasympathetic areas of the pelvic plexus. The lower vagina is supplied by the pudendal nerve.[10][15]

Function

Secretions

Vaginal secretions are primarily from the

sanitary napkins are available to absorb or capture menstrual blood.[54]

The Bartholin's glands, located near the vaginal opening, were originally considered the primary source for vaginal lubrication, but further examination showed that they provide only a few drops of mucus.[55] Vaginal lubrication is mostly provided by plasma seepage known as transudate from the vaginal walls. This initially forms as sweat-like droplets, and is caused by increased fluid pressure in the tissue of the vagina (vasocongestion), resulting in the release of plasma as transudate from the capillaries through the vaginal epithelium.[55][56][57]

Before and during

fertile environment in the vaginal canal that is favorable to the survival of sperm.[58] Following menopause, vaginal lubrication naturally decreases.[59]

Sexual stimulation

Nerve endings in the vagina can provide pleasurable sensations when the vagina is stimulated during sexual activity. Women may derive pleasure from one part of the vagina, or from a feeling of closeness and fullness during vaginal penetration.[60] Because the vagina is not rich in nerve endings, women often do not receive sufficient sexual stimulation, or orgasm, solely from vaginal penetration.[60][61][62] Although the literature commonly cites a greater concentration of nerve endings and therefore greater sensitivity near the vaginal entrance (the outer one-third or lower third),[61][62][63] some scientific examinations of vaginal wall innervation indicate no single area with a greater density of nerve endings.[64][65] Other research indicates that only some women have a greater density of nerve endings in the anterior vaginal wall.[64][66] Because of the fewer nerve endings in the vagina, childbirth pain is significantly more tolerable.[62][67][68]

Pleasure can be derived from the vagina in a variety of ways. In addition to

sex toys, such as a vibrator or dildo, for vaginal pleasure.[76]

Most women require direct stimulation of the clitoris to orgasm.[61][62] The clitoris plays a part in vaginal stimulation. It is a sex organ of multiplanar structure containing an abundance of nerve endings, with a broad attachment to the pubic arch and extensive supporting tissue to the labia. Research indicates that it forms a tissue cluster with the vagina. This tissue is perhaps more extensive in some women than in others, which may contribute to orgasms experienced vaginally.[61][77][78]

During sexual arousal, and particularly the stimulation of the clitoris, the walls of the vagina lubricate. This begins after ten to thirty seconds of sexual arousal, and increases in amount the longer the woman is aroused.

greater pelvis, and the cervix is elevated above the vaginal floor, resulting in tenting of the mid-vaginal plane.[79] This is known as the tenting or ballooning effect.[81] As the elastic walls of the vagina stretch or contract, with support from the pelvic muscles, to wrap around the inserted penis (or other object),[63] this creates friction for the penis and helps to cause a man to experience orgasm and ejaculation, which in turn enables fertilization.[82]

An area in the vagina that may be an erogenous zone is the G-spot. It is typically defined as being located at the anterior wall of the vagina, a couple or few inches in from the entrance, and some women experience intense pleasure, and sometimes an orgasm, if this area is stimulated during sexual activity.[64][66] A G-spot orgasm may be responsible for female ejaculation, leading some doctors and researchers to believe that G-spot pleasure comes from the Skene's glands, a female homologue of the prostate, rather than any particular spot on the vaginal wall; other researchers consider the connection between the Skene's glands and the G-spot area to be weak.[64][65][66] The G-spot's existence (and existence as a distinct structure) is still under dispute because reports of its location can vary from woman to woman, it appears to be nonexistent in some women, and it is hypothesized to be an extension of the clitoris and therefore the reason for orgasms experienced vaginally.[64][67][78]

Childbirth

The vagina is the birth canal for the

premature rupture of membranes, which occurs in 10% of cases.[84] Among women giving birth for the first time, Braxton Hicks contractions are mistaken for actual contractions,[85] but they are instead a way for the body to prepare for true labor. They do not signal the beginning of labor,[86] but they are usually very strong in the days leading up to labor.[85][86]

As the body prepares for childbirth, the cervix softens, thins, moves forward to face the front, and begins to open. This allows the fetus to settle into the pelvis, a process known as lightening.[87] As the fetus settles into the pelvis, pain from the sciatic nerves, increased vaginal discharge, and increased urinary frequency can occur.[87] While lightening is likelier to happen after labor has begun for women who have given birth before, it may happen ten to fourteen days before labor in women experiencing labor for the first time.[88]

The fetus begins to lose the support of the cervix when contractions begin. With cervical dilation reaching 10 cm to accommodate the head of the fetus, the head moves from the uterus to the vagina.[83][89] The elasticity of the vagina allows it to stretch to many times its normal diameter in order to deliver the child.[90]

Vaginal births are more common, but if there is a risk of complications a

edematous) and is thin, with few rugae, a little after birth. The mucosa thickens and rugae return in approximately three weeks once the ovaries regain usual function and estrogen flow is restored. The vaginal opening gapes and is relaxed, until it returns to its approximate pre-pregnant state six to eight weeks after delivery, known as the postpartum period; however, the vagina will continue to be larger in size than it was previously.[92]

After giving birth, there is a phase of vaginal discharge called lochia that can vary significantly in the amount of loss and its duration but can go on for up to six weeks.[93]

Vaginal microbiota

Gram stain of lactobacilli and squamous epithelial cells in vaginal swab

The vaginal flora is a complex ecosystem that changes throughout life, from birth to menopause. The vaginal microbiota resides in and on the outermost layer of the vaginal epithelium.[45] This microbiome consists of species and genera, which typically do not cause symptoms or infections in women with normal immunity. The vaginal microbiome is dominated by Lactobacillus species.[94] These species metabolize glycogen, breaking it down into sugar. Lactobacilli metabolize the sugar into glucose and lactic acid.[95] Under the influence of hormones, such as estrogen, progesterone and follicle-stimulating hormone (FSH), the vaginal ecosystem undergoes cyclic or periodic changes.[95]

Clinical significance

Pelvic examinations

speculum used in gynecological examination
bivalved vaginal speculum
. The blades of the speculum are above and below and stretched vaginal walls are seen on the left and right.

Vaginal health can be assessed during a pelvic examination, along with the health of most of the organs of the female reproductive system.[96][97][98] Such exams may include the Pap test (or cervical smear). In the United States, Pap test screening is recommended starting around 21 years of age until the age of 65.[99] However, other countries do not recommend pap testing in non-sexually active women.[100] Guidelines on frequency vary from every three to five years.[100][101][102] Routine pelvic examination on adult women who are not pregnant and lack symptoms may be more harmful than beneficial.[103] A normal finding during the pelvic exam of a pregnant women is a bluish tinge to the vaginal wall.[96]

Pelvic exams are most often performed when there are unexplained symptoms of discharge, pain, unexpected bleeding or urinary problems.

cavity search.[106]

Lacerations or other injuries to the vagina can occur during sexual assault or other sexual abuse.[4][96] These can be tears, bruises, inflammation and abrasions. Sexual assault with objects can damage the vagina and X-ray examination may reveal the presence of foreign objects.[4] If consent is given, a pelvic examination is part of the assessment of sexual assault.[107] Pelvic exams are also performed during pregnancy, and women with high risk pregnancies have exams more often.[96][108]

Medications

antifungals. Vaginal rings can also be used to deliver medication, including birth control in contraceptive vaginal rings. These are inserted into the vagina and provide continuous, low dose and consistent drug levels in the vagina and throughout the body.[111][112]

Before the baby emerges from the womb, an injection for pain control during childbirth may be administered through the vaginal wall and near the pudendal nerve. Because the pudendal nerve carries motor and sensory fibers that innervate the pelvic muscles, a pudendal nerve block relieves birth pain. The medicine does not harm the child, and is without significant complications.[113]

Infections, diseases, and safe sex

Vaginal infections or diseases include

antibiotics, poor diet, and stress (such as from a lack of sleep).[115][116] Any of these changes to the acidic balance of the vagina may contribute to yeast infection.[115] An elevated pH (greater than 4.5) of the vaginal fluid can be caused by an overgrowth of bacteria as in bacterial vaginosis, or in the parasitic infection trichomoniasis, both of which have vaginitis as a symptom.[95][117] Vaginal flora populated by a number of different bacteria characteristic of bacterial vaginosis increases the risk of adverse pregnancy outcomes.[118] During a pelvic exam, samples of vaginal fluids may be taken to screen for sexually transmitted infections or other infections.[96][119]

Because the vagina is self-cleansing, it usually does not need special hygiene.

conditioned reflex or disease.[124] Vaginal discharge due to yeast infection is usually thick, creamy in color and odorless, while discharge due to bacterial vaginosis is gray-white in color, and discharge due to trichomoniasis is usually a gray color, thin in consistency, and has a fishy odor. Discharge in 25% of the trichomoniasis cases is yellow-green.[123]

human papillomavirus (HPV), genital herpes and trichomoniasis are some STIs that may affect the vagina, and health sources recommend safe sex (or barrier method) practices to prevent the transmission of these and other STIs.[126][127] Safe sex commonly involves the use of condoms, and sometimes female condoms (which give women more control). Both types can help avert pregnancy by preventing semen from coming in contact with the vagina.[128][129] There is, however, little research on whether female condoms are as effective as male condoms at preventing STIs,[129] and they are slightly less effective than male condoms at preventing pregnancy, which may be because the female condom fits less tightly than the male condom or because it can slip into the vagina and spill semen.[130]

The vaginal lymph nodes often trap cancerous cells that originate in the vagina. These nodes can be assessed for the presence of disease. Selective surgical removal (rather than total and more invasive removal) of vaginal lymph nodes reduces the risk of complications that can accompany more radical surgeries. These selective nodes act as sentinel lymph nodes.[49] Instead of surgery, the lymph nodes of concern are sometimes treated with radiation therapy administered to the patient's pelvic, inguinal lymph nodes, or both.[131]

Vaginal cancer and vulvar cancer are very rare, and primarily affect older women.[132][133] Cervical cancer (which is relatively common) increases the risk of vaginal cancer,[134] which is why there is a significant chance for vaginal cancer to occur at the same time as, or after, cervical cancer. It may be that their causes are the same.[134][132][135] Cervical cancer may be prevented by pap smear screening and HPV vaccines, but HPV vaccines only cover HPV types 16 and 18, the cause of 70% of cervical cancers.[136][137] Some symptoms of cervical and vaginal cancer are dyspareunia, and abnormal vaginal bleeding or vaginal discharge, especially after sexual intercourse or menopause.[138][139] However, most cervical cancers are asymptomatic (present no symptoms).[138] Vaginal intracavity brachytherapy (VBT) is used to treat endometrial, vaginal and cervical cancer. An applicator is inserted into the vagina to allow the administration of radiation as close to the site of the cancer as possible.[140][141] Survival rates increase with VBT when compared to external beam radiation therapy.[140] By using the vagina to place the emitter as close to the cancerous growth as possible, the systemic effects of radiation therapy are reduced and cure rates for vaginal cancer are higher.[142] Research is unclear on whether treating cervical cancer with radiation therapy increases the risk of vaginal cancer.[134]

Effects of aging and childbirth

Age and hormone levels significantly correlate with the pH of the vagina.

hormone replacement therapy), or 4.5–5.0 with hormone replacement therapy.[145]

Side-by-side illustration depicting thinning effects of menopause on musoca of vaginal wall
Pre-menopausal vaginal mucosa (left) versus menopausal vaginal mucosa (right)

After menopause, the body produces less estrogen. This causes

vaginal dryness (a decrease in lubrication).[149] Vaginal dryness can cause discomfort on its own or discomfort or pain during sexual intercourse.[149][150] Hot flashes are also characteristic of menopause.[116][151] Menopause also affects the composition of vaginal support structures. The vascular structures become fewer with advancing age.[152] Specific collagens become altered in composition and ratios. It is thought that the weakening of the support structures of the vagina is due to the physiological changes in this connective tissue.[153]

Menopausal symptoms can be eased by estrogen-containing vaginal creams,

Femring,[154] or other hormone replacement therapies,[151] but there are risks (including adverse effects) associated with hormone replacement therapy.[155][156] Vaginal creams and vaginal estrogen rings may not have the same risks as other hormone replacement treatments.[157] Hormone replacement therapy can treat vaginal dryness,[154] but a personal lubricant may be used to temporarily remedy vaginal dryness specifically for sexual intercourse.[150] Some women have an increase in sexual desire following menopause.[149] It may be that menopausal women who continue to engage in sexual activity regularly experience vaginal lubrication similar to levels in women who have not entered menopause, and can enjoy sexual intercourse fully.[149] They may have less vaginal atrophy and fewer problems concerning sexual intercourse.[158]

Vaginal changes that happen with aging and childbirth include mucosal redundancy, rounding of the posterior aspect of the vagina with shortening of the distance from the distal end of the anal canal to the vaginal opening,

stress urinary incontinence, rectocele, and cystocele.[159] Physical changes resulting from pregnancy, childbirth, and menopause often contribute to stress urinary incontinence. If a woman has weak pelvic floor muscle support and tissue damage from childbirth or pelvic surgery, a lack of estrogen can further weaken the pelvic muscles and contribute to stress urinary incontinence.[160] Pelvic organ prolapse, such as a rectocele or cystocele, is characterized by the descent of pelvic organs from their normal positions to impinge upon the vagina.[161][162] A reduction in estrogen does not cause rectocele, cystocele or uterine prolapse, but childbirth and weakness in pelvic support structures can.[158] Prolapse may also occur when the pelvic floor becomes injured during a hysterectomy, gynecological cancer treatment, or heavy lifting.[161][162] Pelvic floor exercises such as Kegel exercises can be used to strengthen the pelvic floor muscles,[163] preventing or arresting the progression of prolapse.[164] There is no evidence that doing Kegel exercises isotonically or with some form of weight is superior; there are greater risks with using weights since a foreign object is introduced into the vagina.[165]

During the third stage of labor, while the infant is being born, the vagina undergoes significant changes. A gush of blood from the vagina may be seen right before the baby is born. Lacerations to the vagina that can occur during birth vary in depth, severity and the amount of adjacent tissue involvement.

suturing.[168][169] Lacerations from labor do not always occur.[45]

Surgery

The vagina, including the vaginal opening, may be altered as a result of surgeries such as an episiotomy,

urogynecologist to diagnose possible vaginal disorders.[159] With regard to labiaplasty, reduction of the labia minora is quick without hindrance, complications are minor and rare, and can be corrected. Any scarring from the procedure is minimal, and long-term problems have not been identified.[159]

During an episiotomy, a surgical incision is made during the second stage of labor to enlarge the vaginal opening for the baby to pass through.[45][140] Although its routine use is no longer recommended,[171] and not having an episiotomy is found to have better results than an episiotomy,[45] it is one of the most common medical procedures performed on women. The incision is made through the skin, vaginal epithelium, subcutaneous fat, perineal body and superficial transverse perineal muscle and extends from the vagina to the anus.[172][173] Episiotomies can be painful after delivery. Women often report pain during sexual intercourse up to three months after laceration repair or an episiotomy.[168][169] Some surgical techniques result in less pain than others.[168] The two types of episiotomies performed are the medial incision and the medio-lateral incision. The median incision is a perpendicular cut between the vagina and the anus and is the most common.[45][174] The medio-lateral incision is made between the vagina at an angle and is not as likely to tear through to the anus. The medio-lateral cut takes more time to heal than the median cut.[45]

Vaginectomy is surgery to remove all or part of the vagina, and is usually used to treat malignancy.[170] Removal of some or all of the sexual organs can result in damage to the nerves and leave behind scarring or adhesions.[175] Sexual function may also be impaired as a result, as in the case of some cervical cancer surgeries. These surgeries can impact pain, elasticity, vaginal lubrication and sexual arousal. This often resolves after one year but may take longer.[175]

Women, especially those who are older and have had multiple births, may choose to surgically correct vaginal laxity. This surgery has been described as vaginal tightening or rejuvenation.[176] While a woman may experience an improvement in self-image and sexual pleasure by undergoing vaginal tightening or rejuvenation,[176] there are risks associated with the procedures, including infection, narrowing of the vaginal opening, insufficient tightening, decreased sexual function (such as pain during sexual intercourse), and rectovaginal fistula. Women who undergo this procedure may unknowingly have a medical issue, such as a prolapse, and an attempt to correct this is also made during the surgery.[177]

Surgery on the vagina can be elective or cosmetic. Women who seek cosmetic surgery can have

sex reassignment surgeries are available to transgender people. Although not all intersex conditions require surgical treatment, some choose genital surgery to correct atypical anatomical conditions.[179]

Anomalies and other health issues

urinary bladder
(1), uterus (2), and vagina (3)

vaginal agenesis, the external genitalia may appear normal.[185]

Abnormal openings known as

congenital.[191] Various surgical methods are employed to repair fistulas.[192][186] Untreated, fistulas can result in significant disability and have a profound impact on quality of life.[186]

vaginal hysterectomy and occurs when the vaginal cuff ruptures, allowing the small intestine to protrude from the vagina.[107][193]

Müllerian cysts, Gartner's duct cysts, and epidermoid cysts.[197][198] A vaginal cyst is most likely to develop in women between the ages of 30 and 40.[194] It is estimated that 1 out of 200 women has a vaginal cyst.[194][199] The Bartholin's cyst is of vulvar rather than vaginal origin,[200] but it presents as a lump at the vaginal opening.[201] It is more common in younger women and is usually without symptoms,[202] but it can cause pain if an abscess forms,[202] block the entrance to the vulval vestibule if large,[203] and impede walking or cause painful sexual intercourse.[202]

Society and culture

Perceptions, symbolism and vulgarity

Various perceptions of the vagina have existed throughout history, including the belief it is the center of

evolutionary psychologist, stated that because a penis is significantly larger than a clitoris and is readily visible while the vagina is not, and males urinate through the penis, boys are taught from childhood to touch their penises while girls are often taught that they should not touch their own genitalia, which implies that there is harm in doing so. Buss attributed this as the reason many women are not as familiar with their genitalia, and that researchers assume these sex differences explain why boys learn to masturbate before girls and do so more often.[207]

The word vagina is commonly avoided in conversation,

job inequality), which she categorized as being treated like a second-class citizen.[208]

Photograph of a large stone yoni in a museum display case
The womb represents a powerful symbol as the yoni in Hinduism. Pictured is a stone yoni found in Cát Tiên sanctuary, Lam Dong, Vietnam.

Negative views of the vagina are simultaneously contrasted by views that it is a powerful symbol of female sexuality, spirituality, or life. Author Denise Linn stated that the vagina "is a powerful symbol of womanliness, openness, acceptance, and receptivity. It is the inner valley spirit".[212] Sigmund Freud placed significant value on the vagina,[213] postulating the concept that vaginal orgasm is separate from clitoral orgasm, and that, upon reaching puberty, the proper response of mature women is a changeover to vaginal orgasms (meaning orgasms without any clitoral stimulation). This theory made many women feel inadequate, as the majority of women cannot achieve orgasm via vaginal intercourse alone.[214][215][216] Regarding religion, the womb represents a powerful symbol as the yoni in Hinduism, which represents "the feminine potency", and this may indicate the value that Hindu society has given female sexuality and the vagina's ability to deliver life;[217] however, yoni as a representation of "womb" is not the primary denotation.[218]

While, in ancient times, the vagina was often considered equivalent (

green sickness, and possibly for female hysteria. Reported methods for treatment included a midwife rubbing the walls of the vagina or insertion of the penis or penis-shaped objects into the vagina. Symptoms of the female hysteria diagnosis – a concept that is no longer recognized by medical authorities as a medical disorder – included faintness, nervousness, insomnia, fluid retention, heaviness in abdomen, muscle spasm, shortness of breath, irritability, loss of appetite for food or sex, and a propensity for causing trouble.[220] It may be that women who were considered suffering from female hysteria condition would sometimes undergo "pelvic massage" – stimulation of the genitals by the doctor until the woman experienced "hysterical paroxysm" (i.e., orgasm). In this case, paroxysm was regarded as a medical treatment, and not a sexual release.[220]

The vagina and vulva have been given many vulgar names, three of which are

feminists of the 1970s sought to eliminate disparaging terms such as cunt.[225] Twat is widely used as a derogatory epithet, especially in British English, referring to a person considered obnoxious or stupid.[226][227] Pussy can indicate "cowardice or weakness", and "the human vulva or vagina" or by extension "sexual intercourse with a woman".[228] In contemporary English, use of the word pussy to refer to women is considered derogatory or demeaning, treating people as sexual objects.[229]

In contemporary literature and art

The

motifs of the "talking cunt".[230][231] These tales usually involve vaginas talking by the effect of magic or charms, and often admitting to their lack of chastity.[230] Other folk tales relate the vagina as having teeth – vagina dentata (Latin for "toothed vagina"). These carry the implication that sexual intercourse might result in injury, emasculation, or castration for the man involved. These stories were frequently told as cautionary tales warning of the dangers of unknown women and to discourage rape.[232]

In 1966, the French artist

Dadaist artist Jean Tinguely and Per Olof Ultvedt on a large sculpture installation entitled "hon-en katedral" (also spelled "Hon-en-Katedrall", which means "she-a cathedral") for Moderna Museet, in Stockholm, Sweden. The outer form is a giant, reclining sculpture of a woman which visitors can enter through a door-sized vaginal opening between her spread legs.[233]

The Vagina Monologues, a 1996 episodic play by Eve Ensler, has contributed to making female sexuality a topic of public discourse. It is made up of a varying number of monologues read by a number of women. Initially, Ensler performed every monologue herself, with subsequent performances featuring three actresses; latter versions feature a different actress for every role. Each of the monologues deals with an aspect of the feminine experience, touching on matters such as sexual activity, love, rape, menstruation, female genital mutilation, masturbation, birth, orgasm, the various common names for the vagina, or simply as a physical aspect of the body. A recurring theme throughout the pieces is the vagina as a tool of female empowerment, and the ultimate embodiment of individuality.[234][235]

Influence on modification

Societal views, influenced by tradition, a lack of knowledge on anatomy, or sexism, can significantly impact a person's decision to alter their own or another person's genitalia.[177][236] Women may want to alter their genitalia (vagina or vulva) because they believe that its appearance, such as the length of the labia minora covering the vaginal opening, is not normal, or because they desire a smaller vaginal opening or tighter vagina. Women may want to remain youthful in appearance and sexual function. These views are often influenced by the media,[177][237] including pornography,[237] and women can have low self-esteem as a result.[177] They may be embarrassed to be naked in front of a sexual partner and may insist on having sex with the lights off.[177] When modification surgery is performed purely for cosmetic reasons, it is often viewed poorly,[177] and some doctors have compared such surgeries to female genital mutilation (FGM).[237]

Female genital mutilation, also known as female circumcision or female genital cutting, is genital modification with no health benefits.[238][239] The most severe form is Type III FGM, which is infibulation and involves removing all or part of the labia and the vagina being closed up. A small hole is left for the passage of urine and menstrual blood, and the vagina is opened up for sexual intercourse and childbirth.[239]

Significant controversy surrounds female genital mutilation,[238][239] with the World Health Organization (WHO) and other health organizations campaigning against the procedures on behalf of human rights, stating that it is "a violation of the human rights of girls and women" and "reflects deep-rooted inequality between the sexes".[239] Female genital mutilation has existed at one point or another in almost all human civilizations,[240] most commonly to exert control over the sexual behavior, including masturbation, of girls and women.[239][240] It is carried out in several countries, especially in Africa, and to a lesser extent in other parts of the Middle East and Southeast Asia, on girls from a few days old to mid-adolescent, often to reduce sexual desire in an effort to preserve vaginal virginity.[238][239][240] Comfort Momoh stated it may be that female genital mutilation was "practiced in ancient Egypt as a sign of distinction among the aristocracy"; there are reports that traces of infibulation are on Egyptian mummies.[240]

Custom and tradition are the most frequently cited reasons for the practice of female genital mutilation. Some cultures believe that female genital mutilation is part of a girl's initiation into adulthood and that not performing it can disrupt social and political cohesion.[239][240] In these societies, a girl is often not considered an adult unless she has undergone the procedure.[239]

Other animals

A sheep gives birth vaginally

The vagina is a structure of animals in which the female is

exits through the clitoris, allowing the females to urinate, copulate and give birth through the clitoris.[242] The vagina of the female coyote contracts during copulation, forming a copulatory tie.[243]

Birds, monotremes, and some reptiles have a part of the

jawless fish, there is neither oviduct nor vagina and instead the egg travels directly through the body cavity (and is fertilised externally as in most fish and amphibians). In insects and other invertebrates, the vagina can be a part of the oviduct (see insect reproductive system).[246] Birds have a cloaca into which the urinary, reproductive tract (vagina) and gastrointestinal tract empty.[247] Females of some waterfowl species have developed vaginal structures called dead end sacs and clockwise coils to protect themselves from sexual coercion.[248]

A lack of research on the vagina and other female genitalia, especially for different animals, has stifled knowledge on female sexual anatomy.[249][250] One explanation for why male genitalia is studied more includes penises being significantly simpler to analyze than female genital cavities, because male genitals usually protrude and are therefore easier to assess and measure. By contrast, female genitals are more often concealed, and require more dissection, which in turn requires more time.[249] Another explanation is that a main function of the penis is to impregnate, while female genitals may alter shape upon interaction with male organs, especially as to benefit or hinder reproductive success.[249]

Non-human

microbicides,[251] animal models are not often used in the study of sexually transmitted infections, such as trichomoniasis. Another is that such conditions' causes are inextricably bound to humans' genetic makeup, making results from other species difficult to apply to humans.[254]

See also

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External links

  • Vagina, Anatomical Atlases, an Anatomical Digital Library (2018)
  • Media related to Vaginas at Wikimedia Commons
  • The dictionary definition of vagina at Wiktionary
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