Vaginal intraepithelial neoplasia

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Vaginal intraepithelial neoplasia
SpecialtyOncology

Vaginal intraepithelial neoplasia (VAIN) is a condition that describes

histological findings in the vagina characterized by dysplastic changes.[1]

The disorder is rare and generally has no symptoms.[2] VAIN can be detected by the presence of abnormal cells in a Papanicolaou test (Pap smear).[2]

Like

carcinoma in-situ, or stage 0 vaginal cancer.[3]

Infection with certain types of the

human papillomavirus ("high-risk types") may be associated with up to 80% of cases of VAIN.[4] Vaccinating with HPV vaccine before initial sexual contact has been shown to reduce incidence of VAIN.[5]

References

  1. .
  2. ^ .
  3. ^ a b c Cancer Research UK (2002). The stages of cancer of the vagina Archived 2007-10-07 at the Wayback Machine. CancerHelp UK. Retrieved January 3, 2008.
  4. ^ Cancer Research UK (2002). Risks and causes of vaginal cancer Archived 2007-10-07 at the Wayback Machine. CancerHelp UK. Retrieved January 3, 2008.
  5. ^ "FDA Approves Expanded Uses for Gardasil to Include Preventing Certain Vulvar and Vaginal Cancers". Food and Drug Administration. 2008-09-12. Retrieved 2010-02-13.

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