Corticovirus
Corticovirus | |
---|---|
The assembled capsid made of P2 and P3 proteins.[1] | |
Virus classification | |
(unranked): | Virus |
Realm: | Varidnaviria |
Kingdom: | Bamfordvirae |
Phylum: | Preplasmiviricota |
Class: | Tectiliviricetes |
Order: | Vinavirales |
Family: | Corticoviridae |
Genus: | Corticovirus |
Corticovirus is a genus of
Taxonomy
The genus contains the following species:[6]
- Pseudoalteromonas virus Cr39582
- Pseudoalteromonas virus PM2
Other unassigned phages:[7]
Virology
The virons consist of a round,
The icosahedral capsid (T = 21) is 56
Genome
The genome is not segmented, constitutes 13% of the virus's weight and contains a single molecule of circular,
Transcription is organised into three operons.
Replication of the genome is via a rolling-circle mechanism, initiated by the virus encoded endonuclease P12.[citation needed]
Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
---|---|---|---|---|---|
Corticovirus | Polyhedral | T=21 | Non-enveloped | Circular | Monopartite |
Life cycle
Viral replication is cytoplasmic. Entry into the host cell is achieved by adsorption to the host cell surface followed by fusion of the viral membrane with the outer membrane of the host cell and subsequent genome delivery into the cell interior.[12] DNA-templated transcription is the method of transcription. Bacteria of the genera Pseudoalteromonas, Marinomonas and Vibrio serve as the natural host. Corticovirus PM2 is a lytic virus and at the end of the infection cycle disrupts the host cell using a unique lysis system consisting of phage-encoded proteins P17 and P18 as well as an unidentified host autolysin.[13] However, identification of PM2-like proviruses in bacterial genomes indicates that other members of this family might be temperate viruses. Transmission routes are passive diffusion.[3]
Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
---|---|---|---|---|---|---|---|
Corticovirus | Bacteria | None | Injection | Lysis | Cytoplasm | Cytoplasm | Passive diffusion |
References
- PMID 18775333.
- ^ a b "Corticoviridae". ICTV Online (10th) Report.
- ^ a b "Viral Zone". ExPASy. Retrieved 15 June 2015.
- PMID 17634101.
- PMID 5655723.
- ^ "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 22 May 2021.
- ^ Corticoviridae. NCBI Taxonomy.
- ^ Kiveld, H.M., Kalkkinen, N. and Bamford, D.H. (2002). Bacteriophage PM2 has a protein capsid surrounding a spherical lipid-protein core" J. Virol. 76, 8169-8178.
- ^ Kiveld, H.M., Männistö, R.H., Kalkkinen, N. and Bamford, D.H. (1999). Purification and protein composition of PM2, the first lipid-containing bacterial virus to be isolated" Virology 262, 364-374.
- ^ Harrison, S.C., Caspar, D.L., Camerini-Otero, R.D. and Franklin, R.M. (1971). Lipid and protein arrangement in bacteriophage PM2. Nat. New Biol., 229, 197-201.
- ^ Männistö, R.H., Kivelä, H.M., Paulin, L., Bamford, D.H. and Bamford, J.K.H. (1999). The complete genome sequence of PM2, the first lipid-containing bacterial virus to be isolated" Virology 262, 355-363.
- PMID 20646729.
- PMID 17555443.