Vitamin D3 24-hydroxylase

Source: Wikipedia, the free encyclopedia.
Vitamin D3 24-hydroxylase
Identifiers
ExPASy
NiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

Vitamin D3 24-hydroxylase (EC 1.14.15.16, CYP24A1) is an enzyme with systematic name calcitriol,NADPH:oxygen oxidoreductase (24-hydroxylating).[1][2][3][4][5][6][7] This enzyme catalyses the following chemical reaction

(1) calcitriol + NADPH + H+ + O2 calcitetrol + NADP+ + H2O
(2) calcidiol + NADPH + H+ + O2 secalciferol + NADP+ + H2O

Vitamin D3 24-hydroxylase is a heme-thiolate enzyme (P-450).

References

External links