Vitamin D3 24-hydroxylase
Vitamin D3 24-hydroxylase | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
|
Vitamin D3 24-hydroxylase (EC 1.14.15.16, CYP24A1) is an enzyme with systematic name calcitriol,NADPH:oxygen oxidoreductase (24-hydroxylating).[1][2][3][4][5][6][7] This enzyme catalyses the following chemical reaction
- (1) calcitriol + NADPH + H+ + O2 calcitetrol + NADP+ + H2O
- (2) calcidiol + NADPH + H+ + O2 secalciferol + NADP+ + H2O
Vitamin D3 24-hydroxylase is a heme-thiolate enzyme (P-450).
References
External links
- Vitamin+D3+24-hydroxylase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)