Wada test
Wada test | |
---|---|
Synonyms | Intracarotid sodium amobarbital procedure |
Purpose | establishes cerebral language and memory |
The Wada test, also known as the intracarotid sodium amobarbital procedure (ISAP) or Wada-Milner Test, establishes cerebral language and memory representation of each hemisphere.
Method
Medical professionals conduct the test with the patient awake. A
There is currently great variability in the processes used to administer the test, and so it is difficult to compare results from one patient to the other.[3]
Uses
The test is usually performed prior to
The Wada test has several side-effects. Drastic
Though generally considered a safe procedure, there are at least minimal risks associated with the
]History
The Wada test is named after Japanese neurologist and epileptologist Juhn Atsushi Wada, of the University of British Columbia.[5][6] He developed the test while he was a medical resident in Japan just after[citation needed] World War II, when he was receiving training in neurosurgery. Wada developed the technique of transient hemispheric anesthetization through carotid amytal injection to decrease the cognitive side effects associated with bilateral electroconvulsive therapy.[7] He published the initial description of motor, sensory, language, and effects on the "conscious state" in 1949, in Japanese. During his fellowship at the Montreal Neurological Institute, he introduced the test to Dr. Brenda Milner and associates, who modified the test to assess language laterality and memory function prior to a unilateral lobectomy. As this is now the primary use of the procedure, some neuropsychologists argue for it to be renamed the Wada-Milner Test in recognition of her significant contributions. [8] [9]
Filmography
- Grey's Anatomy season 5, episode 23, Here's to Future Days: Mention of the Wada test at 00:06:13[10] and showing Hollywood's portrayal of the test[11]at 00:12:31.
See also
References
- ^ "Wada Test - Cleveland Clinic". Cleveland Clinic.
- PMID 9240237.
- PMID 16059438.
- ISBN 0-465-02960-4.
- ^ Loring, D.W., Meador, K.J., Lee, G.P., King, D.W. (1992). Amobarbital Effects and Lateralized Brain Function: The Wada Test. New York: Springer-Verlag.
- ^ Wada J (1949). "A new method for the determination of the side of cerebral speech dominance. A preliminary report of the intra-carotid injection of sodium amytal in man". Igaku to Seibutsugaki, Tokyo. 14: 221–222.
- S2CID 5530070.
- ^ Andrew-Gee, Eric (4 May 2023). "Doctor Juhn Wada revolutionized epilepsy surgery (Obituary)". The Globe and Mail. Retrieved 29 December 2023.
- ^ Loring, David; Meador, Kimford. "History of the Wada Test" (PDF). Oxford Handbook of History of Clinical Psychology.
- ^ Here's to Future Days (2009), retrieved 2019-02-03
- ^ Here's to Future Days (2009), retrieved 2019-02-03