Water for injection

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Water for injection
Sterile water for injection
Clinical data
AHFS/Drugs.comFDA Professional Drug Information
License data
ATC code
Identifiers
CAS Number
ChemSpider
UNII
Chemical and physical data
FormulaH2O

Water for injection is

under the skin.[4] A non-sterile version may be used in manufacturing with sterilization occurring later in the production process.[5]

Side effects and mechanisms

The primary use of sterile water for injection is as an ingredient for

In the UK, some hospitals offer subcutaneous injections of water directly for treating back pain in labour. It is controversial, with some claiming it is pseudoscience.[7] Because sterile water is not isotonic, its injection causes acute pain.[8] One purported mechanism of action is to induce acute local pain to compete directly with diffuse back pain through a mechanism called diffuse noxious inhibitory control; another hypothesis is instead that the acute pain releases endorphins.[8] A review and meta-analysis in 2009 found the benefits of its use inconclusive.[8]

History and culture

It is on the

over the counter in the United States.[3]

Other names

Water for injection is also known as aqua ad iniectabilia or aqua ad injectionem.

References

  1. ^ "<1231> Water for Pharmaceutical Purposes" (PDF). hmc.usp.org. p. 2. Archived from the original (PDF) on 11 March 2015. Retrieved 14 January 2017.
  2. .
  3. ^ a b c d "Sterile Water for Injection - FDA prescribing information, side effects and uses". Drugs.com. Archived from the original on 18 January 2017. Retrieved 14 January 2017.
  4. ^ a b "Water for Injection - FDA prescribing information, side effects and uses". Drugs.com. Archived from the original on 16 July 2017. Retrieved 14 January 2017.
  5. ^ from the original on 16 January 2017.
  6. ^ "Sterile Water for Injection, USP" (PDF). Baxter Corporation. U.S. Food and Drug Administration. September 2014.
  7. ISSN 0140-0460
    . Retrieved 30 September 2023.
  8. ^ .
  9. . WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
  10. . WHO/MHP/HPS/EML/2021.02.

External links