Xylopropamine

Source: Wikipedia, the free encyclopedia.
Xylopropamine
Clinical data
Routes of
administration
Oral
ATC code
  • none
Legal status
Legal status
Identifiers
  • (±)-1-(3,4-dimethylphenyl)propan-2-amine
JSmol)
ChiralityRacemic mixture
  • c1c(ccc(c1C)C)CC(N)C
  • InChI=1S/C11H17N/c1-8-4-5-11(6-9(8)2)7-10(3)12/h4-6,10H,7,12H2,1-3H3 ☒N
  • Key:ZSZUWPRERIPUBM-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Xylopropamine (Perhedrin, Esanin), also known as 3,4-dimethylamphetamine, is a

appetite suppressant in the 1950s.[1]

Xylopropamine was briefly sold as the sulfate salt, but it was not widely marketed. Other related amphetamine derivatives such as 2,4-dimethylamphetamine were also investigated for the same purpose, however these drugs had negative side effects such as high blood pressure and were not very successful, mainly due to the introduction of alternative drugs like phentermine which had similar efficacy but fewer side effects.

Xylopropamine was also reported as having analgesic[2] and anti-inflammatory[3] effects but its side effect profile resulted in it never being further developed for these applications.

See also

References

  1. ^ US 2384700, Schnider O, "Alkylated phenyl-isopropyl-amines and process for the manufacture of same", issued 11 September 1945, assigned to Hoffman La Roche 
  2. S2CID 34027366
    .
  3. .