ATP-dependent Clp protease adaptor protein ClpS
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ClpS is an N-recognin in the N-end rule pathway.[1] ClpS interacts with protein substrates that have a bulky hydrophobic residue (leucine, phenylalanine, tyrosine, and tryptophan) at the N-terminus. The protein substrate is then degraded by the ClpAP protease.[2][3]
In molecular biology, the ATP-dependent Clp protease adaptor protein ClpS is a
ClpS is a small alpha/beta protein that consists of three
beta-sheet. Dimerization
of ClpS may occur through its N-terminal domain. This short extended N-terminal region in ClpS is followed by the central seven-residue beta-strand, which is flanked by two other beta-strands in a small beta-sheet.