Adenophostin
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IUPAC name
[(2R,3R,4R,5R)-2-(6-Amino-9-purinyl)-4-[[(2R,3R,4R,5R,6R)-3-hydroxy-6-(hydroxymethyl)-4,5-diphosphonooxy-2-tetrahydropyranyl]oxy]-5-(hydroxymethyl)-3-tetrahydrofuranyl] dihydrogen phosphate
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Identifiers | |
3D model (
JSmol ) |
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ChEMBL | |
ChemSpider | |
IUPHAR/BPS |
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PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C16H26N5O18P3 | |
Molar mass | 669.32 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Adenophostin A is a potent
receptor agonist
, but is much more potent than IP3.
IP3R is a ligand-gated intracellular Ca2+ release channel that plays a central role in modulating cytoplasmic free Ca2+ concentration (Ca2+i). Adenophostin A is structurally different from IP3 but could elicit distinct calcium signals in cells.[1]
References
- PMID 11279251.