Afimoxifene

Afimoxifene
	Topical (gel)
Identifiers
	IUPAC name (Z)-4-(1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenylbut-1-enyl)phenol;
JSmol)	Interactive image;
	SMILES CC\C(c1ccccc1)=C(c2ccc(OCCN(C)C)cc2)/c3ccc(O)cc3;
	InChI InChI=1S/C26H29NO2/c1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h5-17,28H,4,18-19H2,1-3H3/b26-25- ; Key:TXUZVZSFRXZGTL-QPLCGJKRSA-N ;
	(verify)

Afimoxifene, also known as 4-hydroxytamoxifen (4-OHT) and by its tentative brand name TamoGel, is a

cyclical mastalgia,^[5] but further studies are required before afimoxifene can be approved for this indication and marketed.^[4]

Afimoxifene is a SERM and hence acts as a

ERRγ.^[7]^[8]^[9]

References

^ ^a ^b "Afimoxifene - BHR Pharma". AdisInsight. Springer Nature Switzerland AG.
S2CID 21413981
.

^ "Statement on a nonproprietary name adopted by the USAN council: Afimoxifene" (PDF). American Medical Association. Retrieved 2008-03-26.

^
ISBN 978-3-319-46356-8
.

S2CID 22382077
.

PMID 26023144
.

ISBN 978-1-4557-1239-7
.

ISBN 978-1-118-89115-5
.

PMID 16515477
.

External links

4-hydroxytamoxifen at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

Afimoxifene - AdisInsight

v
t
e

Retrieved from "https://en.wikipedia.org/w/index.php?title=Afimoxifene&oldid=1191609653"

[AdisInsight-1] "Afimoxifene - BHR Pharma". AdisInsight. Springer Nature Switzerland AG.

[Desta_2004-2] S2CID 21413981
.

[AMA_USAN-3] "Statement on a nonproprietary name adopted by the USAN council: Afimoxifene" (PDF). American Medical Association. Retrieved 2008-03-26.

[JatoiRody2016-4] 
ISBN 978-3-319-46356-8
.

[pmid17351746-5] S2CID 22382077
.

[pmid26023144-6] PMID 26023144
.

[Levine2011-7] ISBN 978-1-4557-1239-7
.

[Khetan2014-8] ISBN 978-1-118-89115-5
.

[pmid16515477-9] PMID 16515477
.

[5]

[4]

[7]

[8]

[9]

See also

References

External links