Alkaline tide
Alkaline tide (mal del puerco) refers to a condition, normally encountered after eating a meal, where during the production of
During hydrochloric acid secretion in the stomach, the gastric parietal cells extract chloride anions, carbon dioxide, water and sodium cations from the blood plasma and in turn release bicarbonate back into the plasma after forming it from carbon dioxide and water constituents. This is to maintain the plasma's electrical balance, as the chloride anions have been extracted. The bicarbonate content causes the venous blood leaving the stomach to be more alkaline than the arterial blood delivered to it.
The alkaline tide is neutralised by a secretion of H+ into the blood during HCO3− secretion in the pancreas.[2]
Postprandial alkaline tide has also been shown to be a causative agent of
A more pronounced alkaline tide results from vomiting, which stimulates hyperactivity of gastric parietal cells to replace lost stomach acid.[verification needed] Thus, protracted vomiting can result in metabolic alkalosis.[5]
References
- ISBN 978-0-7020-4841-8.
- ISBN 978-0-7020-4841-8.
- PMID 6698874.
- ^ McGavin, MD., Zachary, JF. Pathologic Basis of Veterinary Disease, Fourth Edition, Mosby, 2007, pp. 680–686.
- PMID 4600132.
- Gennari, F. John (2005). Acid-base disorders and their treatment. Informa Health Care. p. 217. ISBN 978-0-8247-5915-5.