Amylin family
| Calc_CGRP_IAPP | |||||||||
|---|---|---|---|---|---|---|---|---|---|
TCDB 1.C.49 | | ||||||||
| OPM superfamily | 243 | ||||||||
| OPM protein | 2jxz | ||||||||
| |||||||||
In molecular biology, the amylin protein family or calcitonin/CGRP/IAPP protein family is a family of proteins, which includes the precursors of
islet amyloid polypeptide (IAPP) and adrenomedullin
.
vasodilatation in a variety of vessels, including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter
or neuromodulator role.
glucose metabolism
. Structurally, IAPP is closely related to CGRP.
Two
xCxxxxxCxxxxxxxxxxxxxxxxxxxxxxxxxxxx-NH(2)
| | Amide group
+-----+
Subfamilies
Human proteins containing this domain
CALCB; IAPP