Benzimidazole fungicide

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Chemical structure of benomyl

Benzimidazole fungicides are a class of

basidiomycetes, but not oomycetes. They are applied to cereals, fruits, vegetables and vines, and are also used in postharvest handling of crops.[1]

The

β-tubulin, a protein important in forming the cytoskeleton, is targeted.[1] They mostly inhibit polymerization of β-tubulin by interacting with it directly, but other interactions also exist.[3]

Starting in the late 1960s, they were widely used to control fungal pathogens such as

Fungicide Resistance Action Committee lists them as having a high risk of resistance evolution.[6]

References

  1. ^ .
  2. ^ .
  3. ^ .
  4. .
  5. ^ Georgopoulos, S. G. (1977). "Pathogens Become Resistant to Chemicals". In Horsfall, James G.; Cowling, Ellis B. (eds.). Plant Disease: An Advanced Treatise. Vol. 1. Academic Press. p. 330.
  6. ^ "FRAC Code List" (PDF). FRAC. 2017. Archived from the original (PDF) on 8 December 2017. Retrieved 8 December 2017.