C. Thomas Caskey
C. Thomas Caskey | |
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Born | |
Died | January 13, 2022 | (aged 83)
Nationality | American |
Alma mater | University of South Carolina, Duke University Medical School |
Awards | William Allan Award (2021) |
Scientific career | |
Fields | Biomedical genetics |
Institutions | Baylor College of Medicine, |
External videos | |
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2021 William Allan Award, American Society of Human Genetics, 2021. |
Charles Thomas Caskey (September 12, 1938 – January 13, 2022), also known as C. Thomas Caskey,
Caskey's research over a period of more than 50 years has focused on the genetic basis of human diseases and their molecular diagnosis. He discovered the molecular basis of disease "anticipation" as an expansion of short tandem repeat DNA sequences causative of FragileX, Myotonic Dystrophy, Ataxia, and now over 40 additional diseases (Giovanni Herenzini Foundation Prize). One of his more widely used discoveries was that of a simple PCR test for DNA evidence at crime scenes that is now standard practice among police services in the western world. (Courage in DNA Award, DOJ). It was first validated to clarify Gulf War casualties.
Education
Caskey attended the
Career
Caskey trained at
In 1971, Caskey left NIH to found the Department of Molecular and Human Genetics at
In 1994 Caskey left academia to become senior vice president for research at Merck Pharmaceuticals and Vaccines. He was trustee and president of The Merck Genome Research Institute at the Merck Research Laboratories in Sumneytown Pike, West Point, Pennsylvania.[5][4]
Caskey has had a long engagement with medical science in other countries, notably Canada, Mexico and China. From 2002 to 2009 he was a member of the Board of
Casked served as director of the Joint Postdoctoral Program between the University of Texas Health Science Center at Houston and Facultad de Medicina y Hospital Universitario de la Universidad Autonoma de Nuevo León and continues to serve as a member of the Scientific Commission to Prevent Epidemic and Emergency Health Issues in Nuevo León. For his service to biotechnology development in Mexico be received the Governor of Nuevo León Award for Cooperation in Education and Investigation (2009) and the "Flame of Truth" award for backing up biotechnology's development in Mexico (2014).[3]
In recent years, his work has also involved cooperation with biomedical researchers in the Taizhou Cardiovascular R&D Centre and the Guangshou Institute of Biomedicine and Health (GIBH), Chinese Academy of Sciences.[5]
Over a period of more than 30 years, Caskey has served as a member or chair of the scientific advisory boards of more than a dozen bio-medical corporations, largely focused on human genetics and related gene therapies for muscular dystrophy and other neuro-muscular diseases. He was a Fellow of the American Society of Microbiology, the American Association for the Advancement of Science, the American College of Medical Geneticsthe American College of Physicians and the Royal Society of Canada. From 1990 to 1991 he served as president of the American Society of Human Genetics, President of the Human Genome Organization (1988-1990) and in 2004–05, President of the Academy of Medicine, Engineering and Science of Texas.[6][5]
In the United States, Caskey has served on advisory boards and review panels for the National Institutes of Health and the Food & Drug Administration, and internationally as a special advisor to the World Health Organization (WHO) Hereditary Diseases Program, and as a member of the WHO's Expert Advisory Panel on Human Genetics.[4][5]
In 2000, Caskey returned to Houston as founding director and
In 2006, Caskey was appointed director and CEO-elect of the Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, part of the University of Texas Health Science Center at Houston, where he created the Texas Therapeutics Institute.[7]
In 2019, Caskey took up a new role as Chief Medical Officer of Human Longevity, a medical technology company based in San Diego, using artificial intelligence to prevent diseases associated with aging.[8][5]
References
- S2CID 247407254.
- ^ "Annual Review of Medicine, Planning Editorial Committee - Volume 70, 2019". Annual Reviews. Retrieved 29 September 2021.
EDITOR OF THE ANNUAL REVIEW OF MEDICINE - VOLUME 70, 2019 : C. Thomas Caskey
- ^ a b c d e "C Thomas Caskey, MD, FACP, FACMG, FRSC". www.bcm.edu. Retrieved 9 December 2019.
- ^ a b c d "Profile - Weill Cornell Medicine - Qatar". qatar-weill.cornell.edu. Retrieved 2021-05-25.
- ^ a b c d e "C Thomas Caskey". www.bloomberg.com. Retrieved 2021-05-25.
- ^ a b "EW Healthcare Partners Team - Tom Caskey". www.ewhealthcare.com. Retrieved 2021-05-25.
- ^ "Dr.C.THOMAS Caskey - Baylor College of Medicine - Allied Academies". alliedacademies.com. Retrieved 2021-05-25.
- ^ "World Expert in Genetics Joins Human Longevity as CMO". www.humanlongevity.com. Archived from the original on 2020-07-22.
External links and sources
- Curriculum Vitae of Caskey on the website of Identigene
- C. Thomas Caskey Will Direct Brown Foundation Institute of Molecular Medicine, announcement by UT Health Science Center