COPASI
| Initial release | October 11, 2004 |
|---|---|
| Stable release | 4.40 (Build 278)
/ May 31, 2023 |
| Repository | |
| Written in | Qt |
| License | Artistic License |
| Website | copasi.org |
COPASI[1] (COmplex PAthway SImulator) is an open-source software application for creating and solving mathematical models of biological processes such as metabolic networks, cell-signaling pathways, regulatory networks, infectious diseases, and many others.
History
COPASI is based on the GepasiBBSRC, and the German Ministry of Education.
Development team
COPASI is the result of an international collaboration between the
Virginia Bioinformatics Institute (USA). The project principal investigators are Pedro Mendes
and Ursula Kummer. The chief software architects are Stefan Hoops and Sven Sahle.
Features
COPASI includes features to define models of biological processes, simulate and analyze these models, generate analysis reports, and import/export models in SBML format.
- Model definition: Models are defined as Rate lawassociated with individual reactions. Models can also include compartments, events, and other global variables that can help specify the dynamics of the system.
- Tasks: Tasks are different types of analysis that can be performed on a model. They include stoichiometric analysis, time course simulation using deterministic and stochastic simulation algorithms, metabolic control analysis, computation of Lyapunov exponent, time scale separation, parameter scans, optimization, and parameter estimation.
- Importing and Exporting: COPASI can read models in SBML format as well as in Gepasi format. COPASI can write models in several different formats including the SBML, source code in the C programming language, Berkeley Madonna files, and XPPAUT Archived 18 April 2022 at the Wayback Machine files.