Caramboxin

Source: Wikipedia, the free encyclopedia.
Caramboxin
Names
IUPAC name
2-Carboxy-3-hydroxy-5-methoxy-L-phenylalanine
Systematic IUPAC name
2-[(2S)-2-Amino-2-carboxyethyl]-6-hydroxy-4-methoxybenzoic acid
Identifiers
3D model (
JSmol
)
ChemSpider
UNII
  • InChI=1S/C11H13NO6/c1-18-6-2-5(3-7(12)10(14)15)9(11(16)17)8(13)4-6/h2,4,7,13H,3,12H2,1H3,(H,14,15)(H,16,17)/t7-/m0/s1
    Key: DYJIDGJHOLTGBO-ZETCQYMHSA-N
  • OC(=O)c1c(O)cc(OC)cc1C[C@H](N)C(=O)O
Properties
C11H13NO6
Molar mass 255.226 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Caramboxin (CBX) is a

glutamatergic ionotropic receptors with potent excitatory, convulsant, and neurodegenerative properties.[2]

A possible interaction between caramboxin and oxalic acid in starfruit can lead to both neurotoxic and nephrotoxic effects. Consuming large amounts of starfruit or its juice on an empty stomach is not recommended, even for individuals with normal kidney function.[4]

References

  1. ^ "Star fruit's chemical curse". Chemical & Engineering News: 28. December 2, 2013.
  2. ^
    PMID 24281890
    .
  3. PMID 28203564
    .
  4. PMID 25949386
    .
Retrieved from "https://en.wikipedia.org/w/index.php?title=Caramboxin&oldid=1175809867"