Cell proliferation

Cell proliferation is the process by which a cell grows and divides to produce two daughter cells.

neurons). Thus, cell proliferation is not synonymous with either cell growth or cell division, despite these terms sometimes being used interchangeably.^[5]

tissue regeneration after damage, or in cancer

.

The total number of cells in a population is determined by the rate of cell proliferation minus the rate of cell death.

Cell size depends on both cell growth and cell division, with a disproportionate increase in the rate of cell growth leading to production of larger cells and a disproportionate increase in the rate of cell division leading to production of many smaller cells. Cell proliferation typically involves balanced cell growth and cell division rates that maintain a roughly constant cell size in the exponentially proliferating population of cells. Cell proliferation occurs by combining cell growth with regular "G1-

diploid

cell progeny.

In single-celled organisms, cell proliferation is largely responsive to the availability of

nutrients in the environment (or laboratory growth medium

).

In

IGF-1

family, which are also considered growth factors, and that function to promote cell proliferation in cells throughout the body that are capable of doing so.

Uncontrolled cell proliferation, leading to an increased proliferation rate, or a failure of cells to arrest their proliferation at the normal time, is a cause of cancer.