Chaetochromin

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Chaetochromin
Clinical data
Other names4548-G05
Identifiers
  • 5,5',6,6',8,8'-Hexahydroxy-2,2',3,3'-tetramethyl-2,2',3,3'-tetrahydro-4H,4'H-9,9'-bibenzo[g]chromene-4,4'-dione
JSmol)
  • CC1C(Oc2cc3c(c(cc(c3c4c5cc6c(c(c5c(cc4O)O)O)C(=O)C(C(O6)C)C)O)O)c(c2C1=O)O)C
  • InChI=1S/C30H26O10/c1-9-11(3)39-19-5-13-21(15(31)7-17(33)23(13)29(37)25(19)27(9)35)22-14-6-20-26(28(36)10(2)12(4)40-20)30(38)24(14)18(34)8-16(22)32/h5-12,31-34,37-38H,1-4H3
  • Key:RHNVLFNWDGWACV-UHFFFAOYSA-N

Chaetochromin, also known as 4548-G05, is an

administer than injected insulin.[1] It was discovered in 1981 in Chaetomium gracile fungi,[2] and its interaction with the insulin receptor was identified in 2014.[1]

Stereochemistry

Chaetochromin A and B are

stereoisomers of this structure, while chaetochromin C and D are related but different compounds.[3] It is not known whether the insulin mimetic effect was found in chaetochromin A or B, or in a mixture.[1]

See also

  • Anti-diabetic medication

References

  1. ^
    PMID 24651808
    .
  2. PMID 7296410
    .
  3. ^ "Chaetochromin". PubChem. U.S. National Library of Medicine.
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