Csaba Horváth (chemical engineer)

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Csaba Horváth
Horvath at Yale's Mason Lab in the late 80s
Born(1930-01-25)January 25, 1930
Szolnok, Hungary
DiedApril 13, 2004(2004-04-13) (aged 74)
New Haven, Connecticut
Known forHigh-performance liquid chromatography
Scientific career
InstitutionsYale University

Csaba Horváth (25 January 1930 – 13 April 2004) was a

Hungarian-American chemical engineer, particularly noted for building the first high-performance liquid chromatograph.[1][2][3]

Early life and education

Csaba Horváth was born in

Ph.D. in 1963.[4]

Career

In 1964 he joined

Yale-New Haven Hospital
of a stroke.

Professor Horvath had an abiding interest in the advancement of the careers of young scientists, and has been memorialized by the establishment of the Csaba Horvath Young Scientist Award for the best presentation by a scientist under the age of 35 at the International Symposium on High Performance Liquid Separations and Related Techniques (HPLC) meeting. The award is sponsored by HPLC, Inc.

Work

Csaba Horváth Memorial Award

Having worked in industry in the pilot plant of

gas-liquid chromatography
in his later career.

However, it was while at Harvard Medical School and Yale School of Medicine that he appreciated the need for analytical separation of biological compounds which could not be vaporized, and this led to the application of his particular understanding of separation processes to vastly improve the performance of liquid chromatography. Thus was created high performance liquid chromatography or HPLC, a technique which became a major field of study (and in which he remained a leading figure), and continued to publish till shortly before his death.

Together with Imre Molnar and Wayne Melander he developed the framework for describing retention mechanisms in reversed phase chromatography (RPLC), employing the framework of the solvophobic theory. As HPLC and RPLC became the preeminent techniques associated with biochemical analysis, many have suggested that Csaba Horvath inexplicably missed inclusion in the ranks of Nobel laureates. He worked on other methods of analytical separation of biological materials, notably

Yale
.

He published about 300 papers and held 9 patents. He was a member of the

United States National Academy of Engineering. He received many other honors and awards and is remembered in the Horváth Laboratory of Separation Science[5] at Innsbruck
.

Personal life

In 1963, Horváth married Valeria Scioscioli in Rome, and they emigrated to the United States. He joined the Physics Research Laboratory at Harvard Medical School. The couple had two daughters.

References

  1. ISSN 0173-0835
    .
  2. ISSN 0003-2700
    .
  3. PMID 15221741
    .
  4. ^ Ettre, Leslie (1 May 2005). "Csaba Horváth and the Development of the First Modern High Performance Liquid Chromatograph". LCGC North America. LCGC North America-05-01-2005. 23 (5): 486–495–486–495. Retrieved 27 October 2022.
  5. ^ "Laboratory of Separation Science". Archived from the original on 2012-12-14. Retrieved 2012-05-05.

Sources

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