Disulfide bond formation protein B
 | This article may be too technical for most readers to understand. (June 2012) |
TCDB 5.A.2 | | ||||||||
| OPM superfamily | 173 | ||||||||
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| OPM protein | 2hi7 | ||||||||
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The DsbB protein oxidizes the periplasmic protein DsbA which in turn oxidizes cysteines in other periplasmic proteins in order to make disulfide bonds.[1] DsbB acts as a redox potential transducer across the cytoplasmic membrane. It is a membrane protein which spans the membrane four times with both the N- and C-termini of the protein are in the cytoplasm. Each of the periplasmic domains of the protein has two essential cysteines. The two cysteines in the first periplasmic domain are in a Cys-X-Y-Cys configuration that is characteristic of the active site of other proteins involved in disulfide bond formation, including DsbA and protein disulfide isomerase.[2]
See also
- Disulfide bond formation protein A
- Disulfide bond formation protein C
References
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