Ecdysteroid
Ecdysteroids are
ecdysterone, turkesterone and 2-deoxyecdysone.[4] These compounds are synthesized in arthropods from dietary cholesterol upon metabolism by the Halloween family of cytochrome P450s.[5] Phytoecdysteroids also appear in many plants mostly as a protection agents (toxins or antifeedants) against herbivore insects.[6][7]
Ecdysterone has been tested on mammals due to the interest in its potential hypertrophic effect. It has been found to increase hypertrophy in rats at a similar level to some
anabolic androgenic steroids and SARM S 1.[8] This is proposed to be through increase of Calcium leading to activation of Akt and protein synthesis in skeletal muscles.[9]
See also
References
- S2CID 221810929.
- PMID 5494238.
- PMID 16580015.
- ^ "Ecdysteroids Information". Examine.com. Retrieved 27 May 2015.
- S2CID 23942645.
- PMID 11393511.
- S2CID 8496934.
- PMID 26060342.)
{{cite journal}}: CS1 maint: DOI inactive as of January 2024 (link - PMID 20363237.
External links
- Ecdybase, The Ecdysone Handbook - a free online ecdysteroids database
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