Epithelial cell rests of Malassez
In dentistry, the epithelial cell rests of Malassez (ERM) or epithelial rests of Malassez (pax epithelialis pediodontii) are part of the
radicular cyst under the influence of various stimuli. They are named after Louis-Charles Malassez (1842–1909) who described them. Some rests become calcified in the periodontal ligament (cementicles
).
ERM plays a role in cementum repair and regeneration.ectodermal origin like bone, fat, cartilage and neuron-like cells.[2]
References
Further reading
- Ten Cate, A.R. (December 1972). "The epithelial cell rests of Malassez and the genesis of the dental cyst". Oral Surgery, Oral Medicine, Oral Pathology. 34 (6): 956–964. PMID 4509005.
- Xiong, Jimin; Mrozik, Krzysztof; Gronthos, Stan; Bartold, P. Mark (20 July 2012). "Epithelial Cell Rests of Malassez Contain Unique Stem Cell Populations Capable of Undergoing Epithelial–Mesenchymal Transition". Stem Cells and Development. 21 (11): 2012–2025. PMID 22122577.
- Ohshima, Mitsuhiro; Yamaguchi, Yoko; Micke, Patrick; Abiko, Yoshimitsu; Otsuka, Kichibee (May 2008). "In Vitro Characterization of the Cytokine Profile of the Epithelial Cell Rests of Malassez". Journal of Periodontology. 79 (5): 912–919. PMID 18454671.
- Shinmura, Yuka; Tsuchiya, Shuhei; Hata, Ken-ichiro; Honda, Masaki J. (December 2008). "Quiescent epithelial cell rests of Malassez can differentiate into ameloblast-like cells". Journal of Cellular Physiology. 217 (3): 728–738. PMID 18663726.
- Li, S.; Ge, S.; Yang, P. (December 2015). "Expression of cytokeratins in enamel organ, junctional epithelium and epithelial cell rests of Malassez". Journal of Periodontal Research. 50 (6): 846–854. .
- Yamanaka, Takenori; Sakamoto, Akihiko; Tanaka, Yoshiharu; Zhang, Yan; Hayashido, Yasutaka; Toratani, Shigeaki; Akagawa, Yasumasa; Okamoto, Tetsuji (2000). "Isolation and serum-free culture of epithelial cells derived from epithelial rests of Malassez in human periodontal ligament". In Vitro Cellular & Developmental Biology - Animal. 36 (8): 548. .
- Davis, Eric M. (December 2018). "A Review of the Epithelial Cell Rests of Malassez on the Bicentennial of Their Description". Journal of Veterinary Dentistry. 35 (4): 290–298. .
- Hasegawa, Naohiko; Kawaguchi, Hiroyuki; Ogawa, Tetsuji; Uchida, Takashi; Kurihara, Hidemi (February 2003). "Immunohistochemical characteristics of epithelial cell rests of Malassez during cementum repair". Journal of Periodontal Research. 38 (1): 51–56. PMID 12558937.