Fibronectin type II domain
| Fibronectin type II domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| OPM superfamily | 115 | ||||||||
| OPM protein | 1h8p | ||||||||
| CDD | cd00062 | ||||||||
| |||||||||
Fibronectin type II domain is a
Type II domain is approximately sixty amino acids long,
Fibronectin type II domain and Lipid bilayer interaction
Fibronectin type II domain is part of the extracellular portions of EphA2 receptor proteins. FN2 domain on EphA2 receptors bears positively-charged components, namely K441 and R443, which attract and almost exclusively bind to anionic lipids such as anionic membrane lipid phosphatidylglycerol.[12] K441 and R443 together make up a membrane-binding motif that allows EphA2 receptors to attach to the cell membrane.[12]
Human proteins containing this domain
- Fibronectin type I domain: PLAT;
References
External links
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