Fluoropyrimidine

Source: Wikipedia, the free encyclopedia.
Structural diagram of pyrimidine, a cyclic aromatic chemical structure of four carbon atoms and two nitrogen atoms, the later in positions 1 and 3
Structural diagram of 5-fluorouracil, a fluoropyrimidine with a single bond from carbon 5 to a fluorine atom and double bonds from both carbons 2 and 4 to oxygen atoms
Left: The structure of pyrimidine with the locants for ring atoms marked. Right: 5-Fluorouracil, a fluoropyrimidine formally named as 5-fluoro-1H,3H-pyrimidine-2,4-dione

Fluoropyrimidines are a general class

anticancer medications
, which include:

Some metabolites of these drugs, such as 5-fluorodeoxyuridylate monophosphate, also have fluoropyrimidine structures in the general sense of the term, but the more specific meaning is typically reserved for substances used as pharmaceuticals.