Fork head domain

Source: Wikipedia, the free encyclopedia.
Fork head domain
SCOP2
2hfh / SCOPe / SUPFAM
CDDcd00059
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
PDB1d5v​, 1e17​, 1jxs​, 1kq8​, 2a3s​, 2c6y​, 2d2w​, 2hdc​, 2hfh​

The fork head domain is a type of protein domain that is often found in transcription factors and whose purpose is to bind DNA.[2]

Function

The fork head protein of

embryogenesis.[5] Members of the class O of forkhead box transcription factors (FoxO) have important roles in metabolism, cellular proliferation, stress tolerance and probably lifespan.[6]

See also

References

  1. PMID 9571051
    .
  2. S2CID 18056224
    .
  3. ^
    PMID 2566386
    .
  4. ^
    S2CID 4363526
    .
  5. ^
    PMID 1356269
    .
  6. S2CID 31546098
    .
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