Glutamate synthase
(Redirected from
Glutamine oxoglutarate aminotransferase
)Glutamate synthase (also known as Glutamine oxoglutarate aminotransferase) is an
α-ketoglutarate, and thus along with glutamine synthetase (abbreviated GS) plays a central role in the regulation of nitrogen assimilation in photosynthetic eukaryotes and prokaryotes.[1][2]
This is of great importance as primary productivity in many marine environments is regulated by the availability of inorganic nitrogen.
The primary sources of inorganic nitrogen used by marine algae are
NADPH-dependent) or ferredoxin (ferredoxin dependent) as reductants.[1] They are called NADH-GOGAT and Fd-GOGAT respectively. In photosynthetic eukaryotes, GS and GOGAT isoenzymes are localized in the cytosol and chloroplast
.
Fd-GOGAT is found strictly in
rhodophytes and in the nucleus of vascular plants, but in both cases its product is active in the chloroplast. NADH-GOGAT is found in the nucleus of vascular plants, fungi, and diatoms, while NADPH-GOGAT is found in non-photosynthetic bacteria and archaea.[1]