Glycochenodeoxycholic acid

Source: Wikipedia, the free encyclopedia.
Glycochenodeoxycholic acid
Names
IUPAC name
N-(3α,7α-Dihydroxy-5β-cholan-24-oyl)glycine
Systematic IUPAC name
{(4R)-4-[(1R,3aS,3bR,4R,5aS,7R,9aS,9bS,11aR)-4,7-Dihydroxy-9a,11a-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanamido}acetic acid
Identifiers
3D model (
JSmol
)
ChemSpider
IUPHAR/BPS
UNII
  • InChI=1S/C26H43NO5/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32)/t15-,16+,17-,18-,19+,20+,21-,24+,25+,26-/m1/s1 ☒N
    Key: GHCZAUBVMUEKKP-GYPHWSFCSA-N ☒N
  • C[C@H](CCC(=O)NCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C
Properties
C26H43NO5
Molar mass 449.62 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Glycochenodeoxycholic acid is a

bile salt formed in the liver from chenodeoxycholic acid and glycine, usually found as the sodium salt.[1][2] It acts as a detergent to solubilize fats for absorption.[citation needed
]

References

  1. PMID 21059682
    .
  2. PMID 18048412
    .


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