Hemosiderinuria

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Hemosiderinuria (syn. haemosiderinuria) is the presence of hemosiderin in urine.

proximal convoluted tubule, where the iron portion is removed and stored in ferritin or hemosiderin
. The tubule cells of the proximal tubule become damaged, slough off with the hemosiderin and are excreted into the urine, producing a "brownish" color. It is usually seen three to four days after the onset of hemolytic conditions.

Hemoglobinuria is another indicator of intravascular hemolysis, but disappears more quickly than hemosiderin, which can remain in the urine for several weeks; therefore, hemosiderinuria is a better marker for intravascular hemolysis.

References

  1. ^ "Hemosiderinuria (Concept Id: C2721579) - MedGen - NCBI". www.ncbi.nlm.nih.gov. Retrieved 8 June 2019.