Individual participant data
Individual participant data (also known as individual patient data, often abbreviated IPD) is raw data from individual participants, and is often used in the context of meta-analysis.
The
IPD meta-analysis
In an IPD meta-analysis, patient-level data from multiple studies or settings are combined to address a certain research question. IPD meta-analyses tend to be common for large-scale and international projects, and they are less limited than aggregate data (AD) meta-analyses in terms of the availability and quality of data they can use.
Common aims for an IPD meta-analysis are
- to evaluate the safety or efficacy of medical interventions [4]
- to identify modifiers of treatment effect
- to evaluate the accuracy of diagnostic tests
- to evaluate the association of prognostic markers [5]
- to develop multivariable prediction models (rules) [5]
- to evaluate the predictive performance of prognostic models [5]
Over the past few decades, meta-analyses conducted with IPD (also known as IPD meta-analyses) have become increasingly popular.[6]
References
External links
- Individual participant data meta-analysis information at the Cochrane website
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