Ionotropic effect
An ionotropic effect is the effect of a transmitter substance or hormone that activates or deactivates
ionotropic receptors (ligand-gated ion channels). The effect can be either positive or negative, specifically a depolarization or a hyperpolarization respectively. This term is commonly confused with an inotropic effect, which refers to a change in the force of contraction (e.g. in heart muscle
) produced by transmitter substances or hormones.
Examples
This term could be used to describe the action of
GABAa receptors
.
References
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