IsrM small RNA
| IsrM sRNA | |
|---|---|
| SO | SO:0000370 |
| PDB structures | PDBe |
The IsrM RNA is a small non-coding RNA discovered in Salmonella pathogenicity island, which is not found in E.coli.[1] It is important for invasion of epithelial cells, intracellular replication inside macrophages, virulence and colonisation in mice. It targets the SopA and HilE mRNAs, virulence factors essential for bacterial invasion. It is a first pathogenicity island-encoded sRNA shown to be directly involved in Salmonella pathogenesis.[2]
References
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