Jacob Lockhart Clarke

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Jacob Augustus Lockhart Clarke (1817 – 25 January 1880) was a British

neurologist who is primarily known for his studies of the brain and the spinal cord
.

Life

As his father died early, young Clarke was brought up by his mother in France. Upon moving to England, he chose the medical profession, to which his elder brother and grandfather belonged, and studied at

Guy’s Hospital, and St Thomas' Hospital. Having obtained the diploma of the Worshipful Society of Apothecaries, he began practice at Pimlico, living with his mother. He became devoted to microscopical research on the brain and nervous system, and applying a new method, and proceeding with extreme care and thoroughness, he established many new facts of structure which had important bearings on the physiology and pathology of the nervous system. His first paper, "Researches into the Structure of the Spinal Cord", was received by the Royal Society on 15 October 1850, and published in their Transactions for 1851. It was illustrated, like many of his subsequent papers, by extremely accurate and valuable drawings by himself, and these have been subsequently reproduced in numerous works.[1]

He received the

London College of Physicians
(1871), and entered upon consulting practice in nervous diseases. He became physician to the Hospital for Epilepsy and Paralysis, but gained no great amount of practice, probably owing to his retired habits, and his having published no book by which the public could judge of his work. He died on 25 January 1880 from
phthisis.[1]

Work

Clarke was the first to establish the location of the

neuropathologist Constantin von Monakow). Clarke is credited with introducing the histological technique of mounting cleared sections of tissue in balsam
media.

He published numerous essays on the anatomy and physiology of the

column of Clarke
or as the "nucleus dorsalis of Clarke") is a name sometimes given for the dorsal nucleus of the spinal cord.

References

Attribution

 This article incorporates text from a publication now in the public domainBettany, George Thomas (1887). "Clarke, Jacob Augustus Lockhart". In Stephen, Leslie (ed.). Dictionary of National Biography. Vol. 10. London: Smith, Elder & Co.

External links