Malcolm Ferguson-Smith

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Malcolm Ferguson-Smith
FRSE
Scientific career
InstitutionsJohns Hopkins University
University of Glasgow
University of Cambridge
Western Infirmary
Websiteresearch.vet.cam.ac.uk/research-staff-directory/principal-investigators/systems-pathology/malcom-ferguson-smith

Malcolm Andrew Ferguson-Smith,

FRSE[2] (born 5 September 1931)[1] is a British geneticist.[3][4]

Early life and education

Ferguson-Smith was born in Glasgow in 1931, the son of physician John Ferguson-Smith and educated at Stowe School.[1] He graduated from the University of Glasgow in 1955 with a Bachelor of Medicine, Bachelor of Surgery degree.

Career and research

In 1955–1956 he was House Physician and House Surgeon at the

Senior House Officer (SHO) and Registrar in Pathology.[citation needed
]

Johns Hopkins

In 1959 he was appointed a

human chromosome diagnostic laboratory in the USA.[5]

Return to Glasgow

In 1961 he returned to the Department of

sex determinant in XX males led to the isolation of the mammalian sex-determining gene twenty-five years later.[5]

Gene mapping

In 1987 he was appointed Professor and Head of the Department of Pathology at University of Cambridge and Director of the East Anglia Regional Genetics Service, where he furthered his research on gene mapping. He retired as Head of Pathology in 1998 and moved to the University Department of Veterinary Medicine. In 2002 he established the Cambridge Resource Centre for Comparative Genomics which produced and distributed chromosome-specific DNA from over 120 species of animals, birds and fish to scientists worldwide for research in biology, evolution and gene mapping. This data allowed comparisons between species to be made and mapped, illuminating the relationships between species and allowing research into genomic evolution.[5]

Publications

  • Translocation of c-abl oncogene in chronic myelocytic leukaemia[6]
  • Early Prenatal Diagnosis (1983)[ISBN missing]
  • Prenatal Diagnosis & Screening (1992)[ISBN missing]
  • Essential Medical Genetics (5 edn, 1997)[ISBN missing]

Awards and honours

In 1998 he was appointed as the scientist member of Lord Phillips' Committee to review the UK Government's original

Creutzfeldt–Jakob disease (CJD) and the actions taken, reporting in 2000.[7]

He was elected

Fellow of the Royal Society of Edinburgh (FRSE) in 1978 and a Fellow of the Royal Society (FRS) in 1983.[1] His papers are held at University of Glasgow.[5]

Personal life

He is the father of Anne Ferguson-Smith, Arthur Balfour Professor of Genetics in Cambridge.

References

  1. ^ a b c d e "FERGUSON-SMITH, Prof. Malcolm Andrew". Who's Who. Vol. 2015 (online Oxford University Press ed.). Oxford: A & C Black. (Subscription or UK public library membership required.)
  2. ^ "Malcolm Ferguson-Smith". royalsociety.org.
  3. ^ Jones E M; Tansey E M, eds. (2014). Clinical Molecular Genetics in the UK c.1975-c.2000. UK: Queen Mary, University of London. freely available as a PDF download from the History of Modern Biomedicine Research Group.
  4. ^ "Codebreakers: Makers of Modern Genetics: the Malcolm Ferguson Smith papers". wellcomelibrary.org. 21 March 2024.
  5. ^ a b c d Tim Powell. "Ferguson-Smith, Malcolm Andrew, b.1931. Geneticist". Bath.ac.uk. Archived from the original on 28 October 2009. Retrieved 26 June 2010.
  6. S2CID 4322151
    .
  7. ^ "BSE inquiry". bseinquiry.gov.uk. Archived from the original on 3 February 2001.

External links

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