Martin Evans
Sir Martin Evans | |
---|---|
Born | Martin John Evans 1 January 1941 Stroud, Gloucestershire, England |
Education |
|
Known for | Discovering embryonic stem cells, and development of the knockout mouse and gene targeting. |
Spouse |
Judith Clare Williams MBE
(m. 1966) |
Children | two sons, one daughter[2] |
Awards |
|
Scientific career | |
Fields | Developmental biology |
Institutions | |
Thesis | Studies on the ribonucleic acid of early amphibian embryos |
Doctoral students | Allan Bradley[3][4] Elizabeth Robertson |
Website | cardiff |
Sir Martin John Evans FRS FMedSci FLSW (born 1 January 1941) is an English biologist[6] who, with Matthew Kaufman, was the first to culture mice embryonic stem cells and cultivate them in a laboratory in 1981. He is also known, along with Mario Capecchi and Oliver Smithies, for his work in the development of the knockout mouse and the related technology of gene targeting, a method of using embryonic stem cells to create specific gene modifications in mice.[7][8] In 2007, the three shared the Nobel Prize in Physiology or Medicine in recognition of their discovery and contribution to the efforts to develop new treatments for illnesses in humans.[9][10][11][12][13]
He won a major scholarship to
Early life and education
Evans was born in
Evans won a major scholarship to
Career and research
He became a lecturer in the
After Kaufman left to take up a professorship in Anatomy in Edinburgh, Evans continued his work, branching out eclectically, "drawn into a number of fascinating fields of biology and medicine."[12] In October 1985, he visited the Whitehead Institute, Cambridge, Massachusetts, for one month of practical work to learn the most recent laboratory techniques.[8][19]
In the 1990s, he was a fellow at
Stem cell research
Evans and Kaufman isolated the
In 1981, Evans and Kaufman published results for experiments in which they described how they isolated embryonic stem cells from
Evans and his collaborators showed that they could introduce a new
Personal life
When Evans was a student in Cambridge he met his wife, Judith Clare Williams,[2] at a lunch held by his aunt, wife of an astronomy professor.[10] After they were engaged, their relationship did not go well and Judith went to live in Canada; however, a year later she returned to England and they married.[10] In 1978, they moved from London to Cambridge with their young children, where they lived for more than 20 years before moving to Cardiff. They have one daughter and two sons.[2][35] Their older son was a student at the University of Cambridge and their younger son was a boarder at Christ Church Cathedral School in Oxford and sang in Christ Church Cathedral choir.[10] Martin's granddaughter has graduated from the University of Nottingham and is now a practicing medicine Yorkshire and Humber.
His wife Judith Clare Williams, granddaughter of
Awards and honours
Evans has won numerous awards including:
- 1990 - Elected an EMBO Member[1]
- 1993 - Elected a Fellow of the Royal Society (FRS)[38]
- 1998 - Founder Fellow of the
- 1999 - The USA charity March of Dimes awarded their annual prize in Developmental Biology for research into embryonic growth jointly to Professor Richard Gardner at the University of Oxford and Evans.[40]
- 2001 - Albert Lasker Award for Basic Medical Research, jointly with Mario Capecchi and Oliver Smithies.[35][41][42]
- 2002 - Honorary doctorate from Mount Sinai School of Medicine, New York, USA.[43]
- 2004 - Appointed Knight Bachelor in the 2004 New Year Honours "for services to medical science".[22]
- 2005 - Honorary doctorate from the University of Bath, England.[44]
- 2007 - Nobel Prize in Physiology or Medicine, jointly with Mario Capecchi and Oliver Smithies.[9]
- 2008 - Honorary doctorate from University College London, England.[45]
- 2009 - Gold Medal of the Royal Society of Medicine[46][47]
- 2009 - Copley Medal of the Royal Society[48]
- 2009 - Member of the Advisory Board of the Faraday Institute[49]
- 2009 - UCL Prize Lecture in Clinical Science
- 2015 - Elected a Fellow of the Learned Society of Wales
References
- ^ a b "Martin Evans EMBO profile". people.embo.org. Heidelberg: European Molecular Biology Organization.
- ^ a b c d e f g "EVANS, Sir Martin (John)". Who's Who. Vol. 2015 (online Oxford University Press ed.). A & C Black. (Subscription or UK public library membership required.)
- ^ Bradley, Allan (1985). Isolation characterization and developmental potential of murine embryo-derived stem cells (PhD thesis). University of Cambridge.
- ^ "Allan Bradley - Wellcome Trust Sanger Institute". Sanger.ac.uk. Archived from the original on 13 November 2013.
- ^ "Martin Evans". Desert Island Discs. 17 February 2008. BBC Radio 4. Retrieved 18 January 2014.
- ^ "Christ College Cambridge Alumni".
- ^ a b c d e f g Stem cell architect is knighted BBC News : Wednesday, 31 December 2003
- ^ S2CID 26951331. (subscription required)
- ^ a b c "The Nobel Prize in Physiology or Medicine 2007". Nobelprize.org. Retrieved 8 October 2007.
- ^ a b c d e f g h i j k l m "Desert Island Discs with Martin Evans". Desert Island Discs. 17 February 2008. BBC. Radio 4.
- ^ "Professor Sir Martin Evans Nobel Prize for Medicine". Cardiff University. Archived from the original on 26 January 2013.
- ^ a b c d e f g h Martin Evans on Nobelprize.org , accessed 11 October 2020 including the Nobel Lecture Embryonic Stem Cells: The Mouse Source Vehicle for Mammalian Genetics and Beyond
- ^ "A celebration of science in the UK: 10 Britons who shaped our world". The Independent. 5 July 2006.
- ^ Wales, The Learned Society of. "Martin Evans". The Learned Society of Wales. Retrieved 30 August 2023.
- ^ Evans, Martin. "Martin Evans FRS, DSc". Cardiff School of Biosciences. Archived from the original on 10 February 2001. Retrieved 27 June 2010.
- EThOS uk.bl.ethos.659008.
- ^ a b "20th Nobel Prize for UCL community". University College London. 8 October 2007. Retrieved 9 October 2007.
- S2CID 4256553.
- ^ "Sir Martin J. Evans: Interview". The Nobel Foundation.
- ^ a b "Staff list: Sir Martin Evans FRS, DSc". School of Biosciences, Cardiff University. Archived from the original on 2 August 2009. Retrieved 1 October 2007.
- ^ Chan, Xuefei (7 December 2007). "Experiences of the Nobel Prize Laureates in Physiology or Medicine". People's Daily. Retrieved 5 April 2008.
- ^ a b "No. 57155". The London Gazette (Supplement). 31 December 2003. p. 1.
- ^ "No. 57391". The London Gazette. 24 August 2004. p. 10694.
- ^ "Nobel Laureate appointed as president at Cardiff University". Cardiff University. Archived from the original on 29 November 2010. Retrieved 25 November 2009.
- ^ "Who's who at Cardiff".[permanent dead link]
- ^ "St Edmund's College - University of Cambridge". www.st-edmunds.cam.ac.uk. Retrieved 10 September 2018.
- ^ a b c d e Hansson, Göran K. "The 2007 Nobel Prize in Physiology or Medicine - Advanced Information". Nobelprize.org. Archived from the original on 16 October 2010. Retrieved 26 June 2010.
- S2CID 4256553.
- PMID 6950406.
- S2CID 4335599.
- S2CID 4241422.
- S2CID 1657244.
- PMID 2573070.
- PMID 1620105.
- ^ a b "2001 Albert Lasker Award - Acceptance remarks by Martin Evans". Lasker Foundation. Archived from the original on 20 March 2012. Retrieved 10 May 2008.
- ^ "No. 53153". The London Gazette (Supplement). 30 December 1992. p. 14.
- ^ "Leader of the Stem Cell Revolution Wins Nobel Prize". Medscape Today. 17 October 2007. Retrieved 2 November 2007.
- ^ "List of Fellows of the Royal Society: 1660–2007: A - J". The Royal Society. Archived from the original on 12 December 2007. Retrieved 9 October 2007.
- ^ "Directory listing". Academy of Medical Sciences. Retrieved 9 October 2007.
- ^ "March of Dimes Prize in Developmental Biology: Previous Recipients" (PDF). March of Dimes. Retrieved 1 October 2007.
- ^ "2001 Albert Lasker Award for Basic Medical Research". Lasker Foundation. Retrieved 10 May 2008.
- ^ "Albert Lasker Award". Cardiff University. Archived from the original on 20 March 2012. Retrieved 10 May 2008.
- ^ "Biography: Professor Sir Martin Evans FRS". Cardiff University. Retrieved 10 May 2008.
- ^ "Summer graduation ceremonies begin today at Bath Abbey". University of Bath. 19 July 2005. Retrieved 8 October 2007.
- ^ "Honorary Degrees". UCL. 16 September 2008.
- ^ "Gold Medal for Nobel Prize winner". Cardiff University. 21 January 2009.[permanent dead link]
- ^ "Gold Medal of the RSM". Royal Society of Medicine. 20 January 2009. Archived from the original on 19 December 2008.
- ^ "Royal Society recognises excellence in science". Royal Society. 14 July 2009.
- Faraday Institute. Archived from the originalon 1 February 2011. Retrieved 8 March 2011.
External links
- Sir Martin J. Evans on Nobelprize.org