Nucleotide universal IDentifier
The nucleotide universal IDentifier (nuID) in molecular biology, is designed to uniquely and globally identify oligonucleotide microarray probes.
Background
Oligonucleotide probes of microarrays that are sequence identical may have different identifiers between manufacturers and even between different versions of the same company's microarray; and sometimes the same identifier is reused and represents a completely different oligonucleotide, resulting in ambiguity and potentially mis-identification of the genes hybridizing to that probe. This also makes data interpretation and integration of different batches of data difficult. nuID was designed to solve these problems. It is a unique, non-
The nuID schema has three significant advantages over using the oligo sequence directly as an identifier: first it is more compact due to the base-64 encoding; second, it has a built-in error detection and self-identification; and third, it can be encrypted in cases where the sequences are preferred not to be disclosed. For more details, please refer to the nuID paper.[1] The implementation nuID encoding and decoding algorithms can be found in the lumi package or at [2]
See also
- Illumina Inc.and its beadArray technology
- lumi Bioconductor package of processing Illumina expression microarray
References
- PMID 17540033.)
{{cite journal}}: CS1 maint: multiple names: authors list (link
External links
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