Orphan virus
An orphan virus is a virus that is not associated with a disease but may possess
pathogenicity.[1]
Some orphan viruses include
TT virus (Anelloviridae).[citation needed
]
Gilbert Dalldorf, a pathologist who showed that
Coxsackie viruses paralyze mice but not humans, indicated that the term ‘orphan’ was created "in a moment of conviviality" by a group of virologists.[2]
Many
enteric cytopathic human orphan viruses, because they were originally not associated with any disease. Even though many of them are associated with severe diseases, the name ECHO still continues to be used.[citation needed
]
See also
- Novel virus
- Reoviridae
- Viral metagenomics
References
- ^ Li L, Delwart E. From orphan virus to pathogen: the path to the clinical lab. Current Opin Virol. 2011 Oct;1(4):282-8. doi: 10.1016/j.coviro.2011.07.006.
- ^ Mortimer, Philip P. "Orphan Viruses, Orphan Diseases: Still the Raw Material for Virus Discovery." Reviews in Medical Virology 23.6 (2013): 337-39. Web.
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