Patching and Capping
 | This article relies largely or entirely on a single source. (March 2017) |
The aggregation of fluorescently tagged
. The aggregation appears as a cap or a patch in the fluorescence microscope and is due to the bivalent nature of antibodies. Patching and capping were critical in demonstrating the fluid nature of plasma membranes.Variations in density within the specimen are amplified to enhance contrast in unstained cells which is especially useful for examining living unpigmented cells. In other words, phase contrast is a contrast-enhancing optical technique that can be used to produce high contrast images such as living cells and subcellular including nuclei and other organelles. One of the major advantages of using phase contrast microscopy is that living cells can be examined in their natural state without being killed, fixed, or especially stained. As a result, biological processes in the cell can be observed and recorded in high contrast with sharp clarity of minute specimen details. When the ligand binds to its specific receptor, the
See also
References
- Patching and Capping: Plasma Membrane Protein Redistribution
- Patching and Capping: Plasma Membrane Protein Redistribution