Philippe Sansonetti

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Philippe Sansonetti
Philippe Sansonetti, in 2014
Born
Philippe Joseph Sansonetti

(1949-04-09) 9 April 1949 (age 75)
Paris, France
Alma mater
AwardsForMemRS (2014)[1]
Louis-Jeantet Prize for Medicine (1994)[2]
Websitewww.hhmi.org/scientists/philippe-j-sansonetti

Philippe J. Sansonetti (born 9 April 1949) is a French microbiologist, professor at the Pasteur Institute and the Collège de France in Paris. He is the director of the Inserm Unit 786 (Microbial colonisation and invasion of mucosa) and of the Institut Pasteur laboratory Pathogénie Microbienne Moléculaire.[3][4][5][6][7][8]

Education

Philippe Sansonetti completed General Microbiology, General Virology and Immunology courses at the Institut Pasteur and received his MS degree in Biochemistry/Microbiology from the

outpatient clinic
(1985–1995) and then becoming its medical director (1995–1999 and 2004–2007). He was chairman of its Departments of Bacteriology and Mycology (1989–1992) and Cell Biology and Infection (2002–2006).

Sansonetti has held several scientific administration positions at INSERM,

French Ministry of Research and Technology, as well as at the World Health Organization
where he was chairman of the Steering committee on Diarrheal Diseases Vaccine Development.

Work and honours

Research performed by Philippe Sansonetti has mainly been focused on the understanding of several aspects of the pathogenesis of

adaptive
responses. He also actively contributes to the development of vaccine candidates against the major shigellae causing dysentery in the developing world.

Sansonetti is the author of over 500 publications in peer-reviewed journals and has served as an editor of several professional publications for many years. He is considered to be one of the founders of the cellular microbiology field and has launched an eponym scientific publication dedicated to this field. His achievements in science have been recognised by numerous awards, including:


He was appointed a Knight of the National Order of the Legion of Honour

French Academy of Medicine. He is also a Howard Hughes Medical Institute scholar. Since 2008, he has held the position of Professor at the Collège de France, recipient of the Microbiology and Infectious Diseases Chair. His nomination for the Royal Society reads:

Sansonetti has pioneered the study of molecular pathogenesis of bacterial infections and cellular microbiology, based on his discovery of the mechanism of cell invasion by Shigella. He has led the field practically and conceptually, by discovering key processes relevant to many pathogens and demonstrating the way in which bacteria subvert eukaryotic cells for their growth. These include actin-dependent entry, cell-to-cell spread, pro-inflammatory apoptosis, intracellular sensing of bacteria, regulation of host responses by post-translational modifications, repression of innate immunity genes, and blocking of T-cell migration. Collectively his work has provided the most complete and unified view of a bacterial-controlled disease process.[1]

References

  1. ^ a b c Professor Philippe Sansonetti ForMemRS, Royal Society
  2. ^ Louis-Jeantet Prize
  3. S2CID 13320019
    .
  4. ^ Philippe Sansonetti's publications indexed by the Scopus bibliographic database. (subscription required)
  5. PMID 15364928
    .
  6. PMID 12527755
    .
  7. S2CID 1320864
    .
  8. S2CID 2898805
    .
  9. ^ Louis-Jeantet Prize
  10. ^ ""El Abarca Prize resalta el protagonismo de la Medicina en la sociedad"". Redacción Médica (in Spanish). Retrieved 2024-02-13.
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