Premorbidity

Source: Wikipedia, the free encyclopedia.

Premorbidity refers to the state of functionality prior to the onset of a disease or illness. It is most often used in relation to psychological function (e.g. premorbid personality or premorbid intelligence), but can also be used in relation to other medical conditions (e.g. premorbid lung function or premorbid heart rate).

Psychology

In

cognitive function
. Changes in personality are common in cases of
frontal lobes,[1] the most famous example of this is the case of Phineas Gage
who survived having a tamping iron shot through his head in a railway construction accident. Declines from premorbid levels of intelligence and other cognitive functions are observed in
mental illnesses such as depression[5] and schizophrenia.[6]

Other usage in psychology include premorbid adjustment which has important implications for the prognosis of mental illness such as schizophrenia.[7] Efforts are also being made to identify premorbid personality profiles for certain illness, such as schizophrenia to determine at risk populations.[8]

Clinical and diagnostic usage

In the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR), paranoid, schizoid, and schizotypal personality disorders may be diagnosed as conditions premorbid to the onset of schizophrenia.[9]

See also

References

  1. doi:10.1037/0090-5550.51.3.257.{{cite journal}}: CS1 maint: multiple names: authors list (link
    )
  2. PMID 19486324.{{cite journal}}: CS1 maint: multiple names: authors list (link
    )
  3. S2CID 27074290.{{cite journal}}: CS1 maint: multiple names: authors list (link
    )
  4. PMID 21842971
    .
  5. PMID 19428120
    .
  6. PMID 21928906.{{cite journal}}: CS1 maint: multiple names: authors list (link
    )
  7. ISBN 0-618-52718-4.{{cite book}}: CS1 maint: multiple names: authors list (link
    )
  8. PMID 19497029
    .
  9. ^ American Psychiatric Association, 2000. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision. Washington, D.C.: American Psychiatric Press, Inc.
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