Propylpyrazoletriol

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Propylpyrazoletriol
Identifiers
  • 4-[2,3-bis(4-hydroxyphenyl)-4-propyl-1H-pyrazol-5-ylidene]cyclohexa-2,5-dien-1-one
JSmol)
  • CCCC1=C(N(NC1=C2C=CC(=O)C=C2)C3=CC=C(C=C3)O)C4=CC=C(C=C4)O
  • InChI=1S/C24H22N2O3/c1-2-3-22-23(16-4-10-19(27)11-5-16)25-26(18-8-14-21(29)15-9-18)24(22)17-6-12-20(28)13-7-17/h4-15,25,28-29H,2-3H2,1H3
  • Key:UOSWGERPQQOSHS-UHFFFAOYSA-N

Propylpyrazoletriol (PPT) is a

scientific research to study the function of ERα.[2][3][4] Though originally thought to be highly selective for ERα, PPT has subsequently been found to also act as an agonist of the GPER (GPR30).[5]

See also

References

  1. ISBN 978-3-527-62330-3
    .
  2. ISBN 978-0-12-397769-4
    .
  3. PMID 20977477
    .
  4. ^ Mann MK (2008). Synthesis of Non-steroidal Estrogen Receptor Proteolysis Targeting Chimeric Molecules (PROTACS) (Ph.D. thesis). University of Illinois at Urbana-Champaign. pp. 11–.
  5. PMID 24530924
    .
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